The Song Ma region, which is located in the northwestern Vietnam represents the zone of amalgamation between Indochina and South China blocks. Numerous scattered ultramafic rocks occur in this region in association with Early to Middle Palaeozoic greenschists and paragneisses, and all these rocks were subjected to hydrous metamorphism and deformation. Here, we present new field data, mineral chemistry and geochemistry from a suite of hydrated peridotites within the Song Ma region and discuss the tectonic significances of the region. We also combine the available data within the Song Ma region and Indochina–South China blocks to discuss the tectonic evolution of the subduction zone. Based on the results, we suggest that the peridotites from the Song Ma are mantle residues that suffered a high degree of partial melting in a forearc tectonic setting. The present data together with the available data within the Song Ma region and the Indochina and South China blocks clearly represent a southward directed Middle Palaeozoic subduction system. The Middle Palaeozoic subduction and accretion events mark the evolutionary history along an active convergent margin between the Indochina and South China blocks, possibly related to the amalgamation of the Pangaea supercontinent. Copyright © 2015 John Wiley & Sons, Ltd.