The Central Role of Cytogenetics in Radiation Biology
Susan M. Bailey,
Stephen R. Kunkel,
Joel S. Bedford
et al.
Abstract:Radiation cytogenetics has a rich history seldom appreciated by those outside the field. Early radiobiology was dominated by physics and biophysical concepts that borrowed heavily from the study of radiation-induced chromosome aberrations. From such studies, quantitative relationships between biological effect and changes in absorbed dose, dose rate and ionization density were codified into key concepts of radiobiological theory that have persisted for nearly a century. This review aims to provide a historical… Show more
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