The CERAD Neuropsychological Assessment Battery Is Sensitive to Alcohol-Related Cognitive Deficiencies in Elderly Patients: A Retrospective Matched Case-Control Study

Kaufmann, Liane; Huber, Stefan; Mayer, Daniel; Moeller, Korbinian; Marksteiner, Josef

doi:10.1017/s1355617717001072

Cited by 3 publications

(1 citation statement)

References 37 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…These age-related changes result in more intoxications and potential harm among older adults, especially if they interact and interfere with their treatments and medications [20][21][22]. Heavy drinking is thus particularly detrimental to older adults' health, including cognition [23][24][25], depression [26], falls [23] and survival [27]. Although many studies show a beneficial association between drinking and health in old age, these findings are probably due to selection effects as older drinkers tend to remain drinking if they are healthy, while recent abstainers (as opposed to life-time abstainers) may be 'sick quitters' [28].…”

Section: Introductionmentioning

confidence: 99%

Cross‐country differences in age trends in alcohol consumption among older adults: a cross‐sectional study of individuals aged 50 years and older in 22 countries

et al. 2020

View full text Add to dashboard Cite

Background and Aims Age‐related changes in physiological, metabolic and medication profiles make alcohol consumption likely to be more harmful among older than younger adults. This study aimed to estimate cross‐national variation in the quantity and patterns of drinking throughout older age, and to investigate country‐level variables explaining cross‐national variation in consumption for individuals aged 50 years and older. Design Cross‐sectional observational study using previously harmonized survey data. Setting Twenty‐two countries surveyed in 2010 or the closest available year. Participants A total of 106 180 adults aged 50 years and over. Measurements Cross‐national variation in age trends were estimated for two outcomes: weekly number of standard drink units (SDUs) and patterns of alcohol consumption (never, ever, occasional, moderate and heavy drinking). Human Development Index and average prices of vodka were used as country‐level variables moderating age‐related declines in drinking. Findings Alcohol consumption was negatively associated with age (risk ratio = 0.98; 95% confidence interval = 0.97, 0.99; P‐value < 0.001), but there was substantial cross‐country variation in the age‐related differences in alcohol consumption [likelihood ratio (LR) test P‐value < 0.001], even after adjusting for the composition of populations. Countries’ development level and alcohol prices explained 31% of cross‐country variability in SDUs (LR test P‐value < 0.001) but did not explain cross‐country variability in the prevalence of heavy drinkers. Conclusions Use and harmful use of alcohol among older adults appears to vary widely across age and countries. This variation can be partly explained both by the country‐specific composition of populations and country‐level contextual factors such as development level and alcohol prices.

show abstract