The cerebellum role in arterial hypertension

Vetcher, Alexandre A.; Zhukov, Kirill V.; Gasparuan, Bagrat A.; Shishonin, Alexander Y.

doi:10.1016/j.mehy.2022.110835

Cited by 10 publications

(2 citation statements)

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“…The TCAAEBC currently considers the human body from the point of the thermodynamics of irreversible processes, considering “good” and “bad” health conditions as positions on the map which describes the energetic behavior of the body. Since, according to the TCAAEBC, the body acquires NGSs as a result of adaptation to continuous misinformation due to OABFRH [ 18 , 19 ].…”

Section: Introductionmentioning

confidence: 99%

Different Trajectories for Diabetes Mellitus Onset and Recovery According to the Centralized Aerobic–Anaerobic Energy Balance Compensation Theory

Vetcher,

Zhukov,

Gasparyan

et al. 2023

Biomedicines

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We recently reported that the restoration of cervical vertebral arterial blood flow access (measured as systolic peak (PS)) to the rhomboid fossa leads to the recovery of the HbA1c level in the case of patients with a pre-Diabetes Mellitus (pre-DM) condition. The theory of centralized aerobic–anaerobic energy balance compensation (TCAAEBC) provides a successful theoretical explanation for this observation. It considers the human body as a dissipative structure. Reported connections between arterial hypertension (AHT) and the level of HbA1c are linked through OABFRH. According to the TCAAEBC, this delivers incorrect information about blood oxygen availability to the cerebellum. The restoration of PS normalizes AHT in 5–6 weeks and HbA1c in 12–13 weeks. In the current study, we demonstrate the model which fits the obtained experimental data. According to the model, pathways of onset and recovery from pre-DM are different. The consequence of these differences is discussed. The great significance of the TCAAEBC for medical practice forces the creation of an appropriate mathematical model, but the required adjustment of the model needs experimental data which can only be obtained from an animal model(s). The essential part of this study is devoted to the analysis of the advantages and disadvantages of widely available common mammalian models for TCAAEBC cases.

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Section: Introductionmentioning

confidence: 99%

Different Trajectories for Diabetes Mellitus Onset and Recovery According to the Centralized Aerobic–Anaerobic Energy Balance Compensation Theory

Vetcher,

Zhukov,

Gasparyan

et al. 2023

Biomedicines

Self Cite

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“…The recently announced centralized aerobic-anaerobic energy balance compensation (CAAEBC) theory, which explains NCD (e.g., LVH) development via the loss of access to information about blood flow from the circulatory system to the rhomboid fossa, has raised some questions about correct ways to prove it [1][2][3]. During LVH, the thickened heart wall can become stiff.…”

Section: Introductionmentioning

confidence: 99%