Hyperbaric Oxygen Therapy (HBOT) has been a recognised treatment for a multitude of injuries for decades and presents significant opportunities for the improvement of wound healing, blood vessel restoration, reduction in recovery time after surgery, treatment of neurological and neurodegenerative disorders, improvement of memory and cognition, sports injury rehabilitation, cartilage regeneration, and overall quality of life. This paper aims to investigate HBOT and its indications for use, both as an adjuvant with other established treatments and independently, in order to provide an overview of treatment avenues with immense possibilities and versatility.