The Cerebral Function Analysing Monitor (Cfam)

Sebel, Peter S.; Maynard, D.E.; Major, E.; Frank, M.

doi:10.1093/bja/55.12.1265

Cited by 30 publications

(7 citation statements)

References 9 publications

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“…The amplitude was calculated from the bandpass-filtered and rectified signal with an algorithm that generates minimum, maximum and median amplitudes that are functionally equivalent to the cerebral function monitor [10] . Continuity measures were determined as the percentage of each minute during which the amplitude of the raw EEG (assessed at 2-second intervals) was above the determined threshold amplitude (10, 25, 50 or 100 V).…”

Section: Analysis Of Eegmentioning

confidence: 99%

Cot-Side Electro-Encephalography and Interstitial Glucose Monitoring during Insulin-Induced Hypoglycaemia in Newborn Lambs

Harris¹,

Battin

Williams

et al. 2008

Neonatology

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Background: The optimal approach to detection and management of neonatal hypoglycaemia remains unclear. Objectives: We sought to demonstrate whether electro-encephalography (EEG) changes could be detected on the amplitude-integrated EEG monitor during induced hypoglycaemia in newborn lambs, and also to determine the accuracy of continuously measured interstitial glucose in this situation. Methods: Needle electrodes were placed in the P3-P4, O1-O2 montages. The interstitial glucose sensor was placed subcutaneously. After 30 min baseline recordings, hypoglycaemia was induced by insulin infusion and blood glucose levels were monitored every 5 min. The infusion was adjusted to reduce blood glucose levels by 0.5 mmol/l every 15 min and then maintain a blood glucose level <1.0 mmol/l for 4 h. EEG parameters analysed included amplitude, continuity and spectral edge frequency. The interstitial and blood glucose levels were compared. Results: All lambs (n = 15, aged 3–11 days) became hypoglycaemic, with median blood glucose levels falling from 6.5 to 1.0 mmol/l, p < 0.0001. There were no detectable changes in any of the measured EEG parameters related to hypoglycaemia, although seizures occurred in 2 lambs. There was moderate agreement between the intermittent blood glucose and continuous interstitial glucose measurements in the baseline, decline, and hypoglycaemia periods (mean difference –0.7 mmol/l, 95% confidence interval, CI, –2.8 to 1.4 mmol/l). However, agreement was poor during reversal of hypoglycaemia (mean difference 4.5 mmol/l, 95% CI –1.1 to 10.7 mmol/l). Conclusions: The cot-side EEG may not be a useful clinical tool in the detection of neurological changes induced by hypoglycaemia. However, continuous interstitial glucose monitoring may be useful in the management of babies at risk of hypoglycaemia.

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Section: Analysis Of Eegmentioning

confidence: 99%

Cot-Side Electro-Encephalography and Interstitial Glucose Monitoring during Insulin-Induced Hypoglycaemia in Newborn Lambs

Harris¹,

Battin

Williams

et al. 2008

Neonatology

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“…There was an initial CFM type called CFAM [22,23] that displayed lines representing the maximum, mean, and minimum amplitudes of the aEEG tracing. This CFM type was helpful for objectively assessing the aEEG margins [24,25].…”

Section: Discussionmentioning

confidence: 99%

Calculation of compact amplitude-integrated EEG tracing and upper and lower margins using raw EEG data

Zhang¹,

Ding²

2013

Health

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Amplitude-integrated EEG (aEEG) is a popular method for monitoring cerebral function. Although various commercial aEEG recorders have been produced, a detailed aEEG algorithm currently is not available. The upper and lower margins in the aEEG tracing are the discriminating features for data inspection and tracing classification. However, most aEEG devices require that these margins be measured semi-subjectively. This paper proposes a step-by-step signal-processing method to calculate a compact aEEG tracing and the upper/lower margin using raw EEG data. The high accuracy of the algorithm was verified by comparison with a recognized commercial aEEG device based on a representative testing dataset composed of 72 aEEG data. The introduced digital algorithm achieved compact aEEG tracing with a small data size. Moreover, the algorithm precisely represented the upper and lower margins in the tracing for objective data interpretation. The described method should facilitate aEEG signal processing and further establish the clinical and experimental application of aEEG methods.

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“…It was used by Sebel et al [17] to monitor the depth of anaesthesia. It produces information that is easy to interpret and that varies with depth of sedation.…”

Section: Practical Recommendationsmentioning

confidence: 99%

“…For patients who experience disturbance in nocturnal sleep, overnight sedation under controlled ventilation is recommended, according to the plan described above [17]. …”

Section: Practical Recommendationsmentioning

confidence: 99%

Untitled

Carrasco

2000

Crit Care

103

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Although many promising objective methods (measuring systems) are available, there are no truly validated instruments for monitoring intensive care unit (ICU) sedation. Auditory evoked potentials can be used only for research in patients with a deep level of sedation. Other measuring systems require further development and validation to be useful in the ICU. Continuing research will provide an objective system to improve the monitoring and controlling of this essential treatment for ICU patients. Subjective methods (scoring systems) that are based on clinical observation have proven their usefulness in guiding sedative therapy. The Glasgow Coma Score modified by Cook and Palma (GCSC) achieves good face validity and reliability, which assures its clinical utility for routine practice and research. Other scales, in particular the Ramsay Scale, can be recommended preferably for clinical use. An accurate use of available instruments can improve the sedative treatment that we deliver to our patients.

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The Cerebral Function Analysing Monitor (Cfam)

Cited by 30 publications

References 9 publications

Cot-Side Electro-Encephalography and Interstitial Glucose Monitoring during Insulin-Induced Hypoglycaemia in Newborn Lambs

Cot-Side Electro-Encephalography and Interstitial Glucose Monitoring during Insulin-Induced Hypoglycaemia in Newborn Lambs

Calculation of compact amplitude-integrated EEG tracing and upper and lower margins using raw EEG data

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