2019
DOI: 10.1111/obr.12949
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The challenge of keeping it off, a descriptive systematic review of high‐quality, follow‐up studies of obesity treatments

Abstract: The aim of this systematic review is to answer the question: Is substantial, stable, and long-term weight loss a viable goal for adults with obesity? To answer this question, we conducted a broad systematic search of non-surgical and non-pharmacological obesity treatment studies with the following strict criteria: (a) minimum 3-year follow-up, (b) 5% body mass lost, (c) no continued interventions in the follow-upperiod, (d) prospective design, and (e) less than 30% attrition from the start of the follow-up per… Show more

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Cited by 103 publications
(81 citation statements)
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“…Preventing weight regain after weight loss (WL) remains the biggest challenge in obesity treatment. Behavioural interventions that address diet and physical activity are moderately effective in the short term, but most individuals experience significant weight regain (returning to baseline values) in the long term . However, successful weight loss maintenance (WLM) is critical to uphold health benefits .…”
Section: Introductionmentioning
confidence: 99%
“…Preventing weight regain after weight loss (WL) remains the biggest challenge in obesity treatment. Behavioural interventions that address diet and physical activity are moderately effective in the short term, but most individuals experience significant weight regain (returning to baseline values) in the long term . However, successful weight loss maintenance (WLM) is critical to uphold health benefits .…”
Section: Introductionmentioning
confidence: 99%
“…Weight-loss programs based on diet, exercise, and obesity drugs can help people lose weight, whereas maintaining weight loss seems to be the greatest challenge. [117][118][119] Even when obesity drugs are used during the maintenance phase, the vast majority regain most of the lost weight. 120 Considering that long-term TTh results in a progressive sustained reduction in obesity markers, combined with data showing that men may be more likely to regain weight after weight loss programs, 20,121 TTh holds tremendous potential as a unique obesity treatment for men.…”
Section: Tth In Comparison To Traditional Obesity Treatmentsmentioning
confidence: 99%
“…Behavioural weight management programmes for the treatment of obesity have been found to be effective in the short‐term, but weight regain is common 1‐5 . In the context of an obesogenic environment, 6 individuals are subjected to an array of internal and external pressures that challenge the continuation of weight management behaviours.…”
Section: Introductionmentioning
confidence: 99%