Depression, depression stigma, and attitude toward psychiatric help are associated factors of suicide in adolescents. As parents are the main decision-makers of receiving professional help for their children’s depression and suicide, parental factors influencing their children’s suicide should be examined. Moreover, parents’ help-seeking attitude for their own mental health problems could affect their children’s mental health problems. Therefore, this study examined the serial mediation of adolescents’ depression, depression stigma, and attitude toward psychiatric help in the relationship between parental attitude toward psychiatric help and the suicidal ideation of their children, using data of 103 parent–child pairs. A cross-sectional study was conducted by employing a self-administered survey. A serial mediation analysis was performed using Amos 25.0. Parental attitude toward psychiatric help directly and indirectly influenced children’s suicidal ideation. Children’s depression stigma, attitude toward psychiatric help, and depression mediated the relationship of parental attitude toward psychiatric help and their children’s suicidal ideation. When parents have a more positive attitude toward psychiatric help, their children’s suicidal ideation become more decreased. Enhancing only parental attitude toward psychiatric help may make a positive change on their children’s suicidal ideation. The study findings imply that when developing and applying youth suicide prevention programs, how parents affect their children’s suicidal ideation should be considered as well as adolescents’ depression stigma, attitude toward psychiatric help, and depression. Given the results of this study, healthcare providers may better evaluate the effectiveness of their intervention programs for preventing adolescents’ suicide.