The Characteristic and Short-Term Prognosis of Tinnitus Associated with Sudden Sensorineural Hearing Loss

Ding, Xiaoqiong; Zhang, Xiaoli; Huang, Zhichun; Xu, Feng

doi:10.1155/2018/6059697

Cited by 22 publications

(24 citation statements)

References 44 publications

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“…Based on the visual analogue scale, the secondary outcomes include improvement of adherence to TCM lifestyle and evaluation of changes in WRS [21], Tinnitus Handicap Inventory (THI) [22] for patients with tinnitus and change in common symptoms, such as dizziness and ear blockage. These outcomes are measured at the first visit and during protocol visits.…”

Section: Methodsmentioning

confidence: 99%

Healthy lifestyle consultation based on traditional Chinese medicine versus routine patient education in the treatment of idiopathic sudden sensorineural hearing loss after failure of systemic therapy: study protocol for a clinical randomised trial

Fei

Zheng

Lai

et al. 2019

Trials

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BackgroundIdiopathic sudden sensorineural hearing loss (ISSNHL) is a major cause of deafness. Despite the advances in systemic therapy, some cases of ISSNHL are untreated, because the exact ISSNHL aetiology is unclear. Traditional Chinese medicine (TCM) has been used to treat diseases for thousands of years and is popular and widely practiced in Asia. TCM includes guidance on a healthy lifestyle. In recent decades, the relationship between lifestyle and disease has been emphasised; an unhealthy lifestyle may lead to illnesses. Thus, this study aims to compare the efficacy of lifestyle modification based on TCM with the usual consultation of ISSNHL after failure of a 2-week systemic therapy to provide a scientific basis for clinical decisions.MethodsThis study is a clinical randomised trial that involves 56 patients diagnosed with ISSNHL but who have had incomplete recovery after initial management (at least 2 weeks of routine Western medical treatment). The study is performed in accordance with the sudden hearing loss clinical guideline of the American Academy of Otolaryngology–Head and Neck Surgery, published in 2012. Participants are randomly distributed into two groups: the healthy lifestyle modification group based on TCM and the control group (1:1 ratio). Patient follow-up lasts for 3 months. The primary outcome measure is the effective rate of hearing improvement, which is defined as the proportion of patients with at least 15 dB of improvement in the average thresholds of hearing loss frequency. The secondary outcome measures are improvements in word recognition score, Tinnitus Handicap Inventory and visual analogue scale for ear blockage and dizziness. Assessments are made at baseline and after lifestyle modification for 1 and 3 months.DiscussionThe efficacy of healthy lifestyle modification based on a TCM programme for patients with ISSNHL with incomplete recovery after failure of initial systemic therapy is determined in this trial. Positive results will provide clinical evidence on the effects of a TCM-based healthy lifestyle, which could be recommended as salvage therapy for patients with ISSNHL.Trial registrationChinese Clinical Trial Registry, ChiCTR-INR-17011459. Registered on 22 May 2017.

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Section: Methodsmentioning

confidence: 99%

Healthy lifestyle consultation based on traditional Chinese medicine versus routine patient education in the treatment of idiopathic sudden sensorineural hearing loss after failure of systemic therapy: study protocol for a clinical randomised trial

Fei

Zheng

Lai

et al. 2019

Trials

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“…A meta-analysis of 11 studies with 314 individuals distressed by tinnitus who were randomly allocated to a waiting period of 6-12 weeks revealed mean decreases in symptoms of 3% to 8% (21). The short-term prognosis of tinnitus may be related to a decrease in the reaction (12)(13)(14). As hearing loss improves, their psychological reaction to tinnitus decreases.…”

Section: Hearing Recovery Is Related To the Short-term Prognosis Of Tmentioning

confidence: 99%

“…Tinnitus in SSNHL patients often lasts for more than 6 months. Although several studies have focused on the prognosis of tinnitus accompanied by SSNHL, the follow-up times were mostly within 1 year (12)(13)(14)(15)(16). Therefore, we investigated the long-term outcomes of tinnitus in 161 patients with SSNHL after standard treatments.…”

Section: Introductionmentioning

confidence: 99%

The Long-term Prognosis of Residual Tinnitus with Idiopathic Sudden Sensorineural Hearing Loss

Diao¹,

Li²,

Ma³

et al. 2020

Preprint

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Objectives:To analyze the factors affecting the long-term prognosis of tinnitus accompanied with unilateral idiopathic sudden sensorineural hearing loss (SSNHL). Design:A cohort study. Setting:Academic hospital. Participants:A total of 161 patients with sudden hearing loss accompanied by tinnitus were enrolled. All the patients had two separate telephone follow-ups and were asked about changes in tinnitus. Main outcome measures:The severity of tinnitus at admission and the outcome at discharge were assessed in terms of the patients' sex, age, level of hearing loss, type of audiogram, and so on. Results and Conclusions:Initial tinnitus level was remarkably associated with tinnitus efficacy at discharge and was an independent risk factor for the long-term prognosis of residual tinnitus after SSNHL (odds ratio 0.722, 95% confidence interval 0.550-0.949, p = 0.019), and the median recovery time was 23.00 ± 3.80 months. KEY POINTS 1. The severity of tinnitus associated with SSNHL is generally not very strong and is mostly classified as levels 3 and 4. 2. Initial tinnitus level was remarkably associated with tinnitus efficacy at discharge. 3. The short-term prognosis of tinnitus may be related to psychological changes caused by hearing recovery. 4. The long-term prognosis of residual tinnitus after SSNHL is related only to the initial tinnitus level. 5. Over time, residual tinnitus will gradually recover, with a median healing time of approximately 2 years.

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“…Based on the visual analogue scale, the secondary outcome includes improvement of adherence to TCM lifestyle, evaluation of changes in word recognition score (WRS) 21 , tinnitus handicap inventory (THI) 22 for patients with tinnitus and change in common symptoms, such as dizziness and ear blockage. These outcomes are measured at the first and during protocol visits.…”

Section: Secondary Outcome Measurementioning

confidence: 99%

Healthy lifestyle consultation based on traditional Chinese medicine versus routine patient education in the treatment of idiopathic sudden sensorineural hearing loss after failure of systemic therapy: Study protocol for a clinical randomised trial

Fei

Zheng

Lai

et al. 2019

Preprint

View full text Add to dashboard Cite

Background: Idiopathic sudden sensorineural hearing loss (ISSNHL) is an important cause of deafness. Despite the advances in systemic therapy, some cases of ISSNHL are untreated, because the exact ISSNHL aetiology is unclear . Traditional Chinese medicine (TCM) has been used for treating diseases for thousands of years and is popular and widely practic ed in Asia. TCM includes guidance on healthy lifestyle. In recent decades, the relationship between lifestyle and disease has been emphasised. Moreover, an unhealthy lifestyle may lead to illnesses . Thus, this study aims to compare the efficacy of lifestyle modification based on TCM with the usual consultation of ISSNHL after failure of a 2 weeks systemic therapy to provide a scientific basis for clinical decisions. Methods: This study is a clinical randomised trial that involves 56 patients diagnosed with ISSNHL but with incomplete recovery after initial management (at least 2 weeks routine Western medical treatment). The study is performed in accordance with the sudden hearing loss clinical guideline of the American Academy of Otolaryngology – Head and Neck Surgery , which is published in 2012 . Participants are randomly distributed into two groups, namely, the healthy lifestyle modification group based on TCM and the control group (1:1 ratio). Patient follow-up lasted for 3 months. The primary outcome measure is the effective rate of hearing improvement, which is defined as the proportion of patients with at least 15 dB improvement in the average thresholds by the hearing loss frequency . The secondary outcome measures are the improvements in word recognition score, tinnitus handicap inventory for tinnitus and visual analogue scale for ear blockage and dizziness. Assessments are made at baseline after lifestyle modification for 1 and 3 months. Discussion: The efficacy of healthy lifestyle modification based on a TCM programme for patients with ISSNHL with incomplete recovery after failure of initial systemic therapy is determined in this trial. Positive results provide clinica l evidence on the effects of TCM - based healthy lifestyle, which could be recommended as salvage therapy for patients with ISSNHL.

show abstract

The Characteristic and Short-Term Prognosis of Tinnitus Associated with Sudden Sensorineural Hearing Loss

Cited by 22 publications

References 44 publications

Healthy lifestyle consultation based on traditional Chinese medicine versus routine patient education in the treatment of idiopathic sudden sensorineural hearing loss after failure of systemic therapy: study protocol for a clinical randomised trial

Healthy lifestyle consultation based on traditional Chinese medicine versus routine patient education in the treatment of idiopathic sudden sensorineural hearing loss after failure of systemic therapy: study protocol for a clinical randomised trial

The Long-term Prognosis of Residual Tinnitus with Idiopathic Sudden Sensorineural Hearing Loss

Healthy lifestyle consultation based on traditional Chinese medicine versus routine patient education in the treatment of idiopathic sudden sensorineural hearing loss after failure of systemic therapy: Study protocol for a clinical randomised trial

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