The characteristics and outcomes of secondary peritonitis in a Tertiary Hospital, Benghazi, Libya

Abdulrahman, Abdugadir Mahmoud; Elgazwi, Khaled; Khudora, Mohammed Ben

doi:10.4103/1947-489x.210275

Cited by 2 publications

(3 citation statements)

References 8 publications

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“…There were more males compared to females in this study. A similar observation has been reported by previous studies [3,[9][10][11][12][13][14][15].…”

Section: Discussionsupporting

confidence: 91%

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Comparison of QSOFA and sirs scores for the prediction of adverse outcomes of secondary peritonitis among patients admitted on the adult surgical ward in a tertiary teaching hospital in Uganda: a prospective cohort study

et al. 2021

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Background SIRS and qSOFA are two ancillary scoring tools that have been used globally, inside and outside of ICU to predict adverse outcomes of infections such as secondary peritonitis. A tertiary teaching hospital in Uganda uses SIRS outside the ICU to identify patients with secondary peritonitis, who are at risk of adverse outcomes. However, there are associated delays in decision making given SIRS partial reliance on laboratory parameters which are often not quickly available in a resource limited emergency setting. In response to the practical limitations of SIRS, the sepsis-3 task force recommends qSOFA as a better tool. However, its performance in patients with secondary peritonitis in comparison to that of SIRS has not been evaluated in a resource limited setting of a tertiary teaching hospital in a low and middle income country like Uganda. Objective To compare the performance of qSOFA and SIRS scores in predicting adverse outcomes of secondary peritonitis among patients on the adult surgical wards in a tertiary teaching hospital in Uganda. Methods This was a prospective cohort study of patients with clinically confirmed secondary peritonitis, from March 2018 to January 2019 at the Accident and Emergency unit and the adult surgical wards of a tertiary teaching hospital in Uganda. QSOFA and SIRS scores were generated for each patient, with a score of ≥2 recorded as high risk, while a score of < 2 recorded as low risk for the adverse outcome respectively. After surgery, patients were followed up until discharge or death. In-hospital mortality and prolonged hospital stay were the primary and secondary adverse outcomes, respectively. Sensitivity, specificity, PPV, NPV and accuracy at 95% confidence interval were calculated for each of the scores using STATA v.13. Results A total of 153 patients were enrolled. Of these, 151(M: F, 2.4:1) completed follow up and were analysed, 2 were excluded. Mortality rate was 11.9%. Fourty (26.5%) patients had a prolonged hospital stay. QSOFA predicted in-hospital mortality with AUROC of 0.52 versus 0.62, for SIRS. Similarly, qSOFA predicted prolonged hospital stay with AUROC of 0.54 versus 0.57, for SIRS. Conclusion SIRS is superior to qSOFA in predicting both mortality and prolonged hospital stay among patients with secondary peritonitis. However, overall, both scores showed a poor discrimination for both adverse outcomes and therefore not ideal tools.

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“…There were more males compared to females in this study. A similar observation has been reported by previous studies [3,[9][10][11][12][13][14][15].…”

Section: Discussionsupporting

confidence: 91%

“…QSOFA predicted mortality with a PPV of 11 SIRS had a superior predictive value, in comparison to qSOFA, for both mortality and prolonged hospital stay resulting from secondary peritonitis (Table 4).…”

Section: Positive and Negative Predictive Valuesmentioning

confidence: 99%

Comparison of QSOFA and sirs scores for the prediction of adverse outcomes of secondary peritonitis among patients admitted on the adult surgical ward in a tertiary teaching hospital in Uganda: a prospective cohort study

et al. 2021

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“…Common etiologic entities of secondary peritonitis (SP) include perforated appendicitis; perforated gastric or duodenal ulcer; perforated (sigmoid) colon caused by diverticulitis, volvulus, or cancer; and strangulation of the small bowel. Necrotizing pancreatitis can also be associated with peritonitis in the case of infection of the necrotic tissue [3].…”

Section: Introductionmentioning

confidence: 99%

Patterns and Early Treatment Outcomes of Peritonitis among Patients Admitted at Dodoma Regional Referral Hospital, Dodoma Region, Tanzania

L¹,

Nm²,

Jm³

2018

J Hepatol Gastroint Dis

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The characteristics and outcomes of secondary peritonitis in a Tertiary Hospital, Benghazi, Libya

Cited by 2 publications

References 8 publications

Comparison of QSOFA and sirs scores for the prediction of adverse outcomes of secondary peritonitis among patients admitted on the adult surgical ward in a tertiary teaching hospital in Uganda: a prospective cohort study

Comparison of QSOFA and sirs scores for the prediction of adverse outcomes of secondary peritonitis among patients admitted on the adult surgical ward in a tertiary teaching hospital in Uganda: a prospective cohort study

Patterns and Early Treatment Outcomes of Peritonitis among Patients Admitted at Dodoma Regional Referral Hospital, Dodoma Region, Tanzania

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