The characteristics of bisphosphonate patients developing bisphosphonate-related osteonecrosis of the jaw attending an OMFS department

Abstract

Bisphosphonates are now widely accepted for the management of medical conditions, including arthritis, osteoporosis and various forms of cancer. Such patients are regularly referred to OMFS departments for dental extractions.

Resection and microvascular reconstruction of bisphosphonate‐related osteonecrosis of the jaw: The role of microvascular reconstruction

“…BRONJ is a risk for anyone receiving bisphosphonates and patients should be warned of this potential outcome. This risk is greater in patients who require intravenous bisphosphonates, people who smoke, taking bisphosphonates for greater than 1 year, and also taking other medications that affect bone turnover, such as steroids or chemotherapy for the primary oncologic disease …”

Viewpoints of dentists on the use of bisphosphonates in rheumatology patients

“…Most BP‐induced side effects are minor and transient (e.g. flu‐like symptoms, digestive disorders), but BP administration has been associated with the risk of one serious side effect, osteonecrosis of the jaw (ONJ). The physiopathology of ONJ is not well understood, although several risk factors have been identified.…”