The Characteristics of Childhood Onset Depression According to Depressive Symptoms, Comorbidities and Quality of Life

Abstract

III. Vetró, Á., Baji, I., Benák, I., Besnyő, M., Csorba, J., Daróczy, G., Dombovári, E.,Kiss, E., Gádoros, J., Kaczvinszky, E., Kapornai, K., Mayer, L., Rimay, T., Skultéty,D., Szabó, K., Tamás, Zs., Székely, J., Kovács, M.. (2009) "Risk factors in childhood onset depression" research design, implementation, proceeding: history of 13 years: experience in grant preparation, writing organization in relation to an American NIMH Grant. Psychiatria Hungarica, 24(1), 6-14.IV. Kiss, E., Kapornai, K., Tamás, Zs., Baji, I., Rimay, T., Mayer, L., Gádoros, J., Barr,C., Stressful life events affect quality of life adversely, and it is worsened by depression. Methodes:We examined the above hypothesis in three samples. Participants were children (ages 7-14) with MDD, and community control kids from elementary schools.Diagnoses (via DSM-IV criteria) and onset dates of disorders were finalized "best estimate" psychiatrists, and based on multiple information sources. The depressive symptoms and effects of comorbidities were examined in depressive sample, and the quality of life was examined in the community sample. Results: Six symptoms increased with age, namely: depressed mood, hypersomnia, psychomotor retardation, fatigue, thoughts of death, and suicidal ideation. Only psychomotor agitation was more frequent in younger children. Anhedonia, insomnia, hypersomnia, and somatic complaints were more frequent among girls, and psychomotor agitation was more frequent among boys.Depressed mood, sleeping problems, psychomotor retardation, suicidal symptoms are significantly more frequent in anxiety group. Irritability and psychomotor agitation is significantly more frequent in the disruptive group. Worthlessness is the most frequent in the disruptive group, and in this group it is the third most frequent symptom. The clinical depression influences the quality of life the most strongly, and the higher depression score goes together with a lower quality of life. Stressful life events influence the quality 6 of life directly and through the depressive symptoms indirectly. Conclusions there are some developmental and gender differences in depressive symptom presentation.Irritability is the most frequent criterion symptom. We also observed stable and elevated rates of irritability, which were concurrent with stable and low rates of anhedonia across all age groups. Somatic complaints should be considered an associated feature of the symptom profile of MDD in pediatric populations. Depressive symptoms are reported to have more negative effects on the quality of life than do stressful life events. 7