The characteristics of registered acupuncture clinical trials enrolling cancer patients

Jin, Ming; Xie, Lulu; Mao, Ni; Wei, Jianzi; Chen, Junchao; Chen, Xuefen; Mao, Huijuan

doi:10.1007/s00520-022-07331-9

Cited by 4 publications

(3 citation statements)

References 22 publications

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“…In another trial, focused on the recovery of 81 gastric cancer patients after surgery, the test group, which received transcutaneous electrical acupoint stimulation (TEAS), reported lower pain and regained gastrointestinal peristalsis faster [105]. The application of acupuncture is also researched in pain relief for cancer patients [112].…”

Section: Acupuncturementioning

confidence: 99%

The use of cannabinoids and alternative therapies in chronic pain management: a narrative review

Łukasik,

Guziak,

Bastrzyk

et al. 2024

Palliat Med Pract

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Palliative care patients experience pain daily which significantly lowers their quality of life. Chronic pain is one of the main reasons why people contact health professionals, and its prevalence is about 20% in Europe and the United States. Comprehensive and sufficient pain management is often limited to medical facilities whereas patients suffering from chronic pain staying in their households often receive incomplete analgesia. Pharmacological recommendations were described with specific indications and contraindications for therapeutic regimens in relation to cancer patients under palliative care. The addition of alternative pain management techniques to the pharmacological treatment can contribute to better pain control and even lower doses of opioids administered. On the other hand, state-of-the-art studies evaluating their efficiency and mechanism of action are missing. This study summarizes a variety of alternative pain management methods and mechanisms behind their analgesic and co-analgesic effects that contribute to maximizing the pharmacological effect of analgesic drugs. This study aimed to gather alternative pain control options and assess their efficiency, status, and potential in palliative care settings. Moreover, this review tries to evaluate whether they are scientifically evidence-based or not.

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Section: Acupuncturementioning

confidence: 99%

The use of cannabinoids and alternative therapies in chronic pain management: a narrative review

Łukasik,

Guziak,

Bastrzyk

et al. 2024

Palliat Med Pract

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“…Therefore, considering the evidence-based practice framework for decision making in clinical practice regarding the use of AA in CINV management, it is necessary to produce more robust scientific evidence using adequately validated and standardized protocols [17,18]. Given these considerations, the present study aimed to develop and validate an AA protocol for CINV management in cancer patients undergoing chemotherapy.…”

Section: Introductionmentioning

confidence: 99%

Development and Validation of an Auricular Acupuncture Protocol for the Management of Chemotherapy-Induced Nausea and Vomiting in Cancer Patients

Paiva,

Moura,

Nogueira

et al. 2024

Healthcare

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Auricular acupuncture (AA) has been used to manage chemotherapy-induced nausea and vomiting (CINV). However, the application of the technique varies widely among the clinical trials that test its effectiveness. The aim of the present study was to develop and clinically validate an AA protocol for the management of CINV in cancer patients. This study was carried out in two stages: (1) development of the AA protocol for the management of CINV and (2) clinical validation of the protocol. The content validity of the protocol was determined by a panel of specialists, with an agreement rate ranging from 85.7% to 100%. In the clinical validation, when administered to cancer patients, the protocol developed has been shown to reduce the incidence, frequency, severity, and length of nausea and vomiting following chemotherapy, as well as the severity of nausea and anticipatory nausea following chemotherapy. This protocol needs to be tested in future studies, including a pilot study with a sham group and a randomized clinical trial, in order to further evaluate its feasibility, acceptability, safety, and clinical usefulness for the management of CINV.

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“…Cervical carcinoma was as one of most frequent tumor and early screening is an important way to detect cervical carcinoma in time, improve the cure rate and reduce mortality. [1][2][3] Long noncoding RNAs (lncRNAs) are a new class of RNAs with a length of more than 200 nucleotides, which are abnormally expressed in tumors and are directly or indirectly related to the occurrence and development of various tumors including cervical carcinoma. [4] In recent years, lncRNAs have received extensive attention in the field of tumor diagnosis and treatment.…”

Section: Introductionmentioning

confidence: 99%

The diagnostic value of lncRNA HOTAIR for cervical carcinoma in vaginal discharge and serum

Liu

2023

Medicine

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There is a lower incidence of cervical carcinoma compared with other common carcinomas, however, the mortality rate of cervical carcinoma is higher, suggesting that the treatment and prognosis of cervical carcinoma are relatively poor. Therefore, cervical carcinoma patients urgently need to find new diagnostic markers for early detection and treatment. One hundred and fifty cervical carcinoma and 100 benign cervical disease patients from 2019 January to 2021 December in Tianjin Central Hospital of Gynecology Obstetrics were selected and 100 healthy women were as normal group. The expression of HOX transcript antisense RNA (HOTAIR) in cervical carcinoma and paracancerous tissue, serum sample was measured by realtime PCR assay. The receiver operating characteristic of HOTAIR for cervical carcinoma was analyzed. The study found that the expression level of HOTAIR in primary cervical carcinoma is closely related to tumor metastasis and prognosis. The expression level of HOTAIR in paracancerous tissue was significantly lower than that in cancer tissue, and the expression level of HOTAIR in vaginal discharge and serum was higher than that in cervical carcinoma patients which was positively correlated with tumor malignancy, meanwhile, HOTAIR was significantly reduced after surgery 3 months both in vaginal discharge and serum. In order to examine the diagnostic efficiency of HOTAIR for cervical carcinoma, we found that the area under curve of vaginal discharge was 0.9723, sensitivity was 92%, specificity was 98%, the area under curve of serum was 0.8518, sensitivity was 79%, and specificity was 94% by receiver operating characteristic analysis. The accuracy were 92.7% and 89.3% in vaginal discharge and serum via certified by cervical carcinoma and benign cervical disease patient and healthy people. The above results show that the diagnostic performance of HOTAIR in vaginal discharge is higher than that of serum, and it is expected to become a marker for cervical carcinoma diagnosis and treatment.

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The characteristics of registered acupuncture clinical trials enrolling cancer patients

Cited by 4 publications

References 22 publications

The use of cannabinoids and alternative therapies in chronic pain management: a narrative review

The use of cannabinoids and alternative therapies in chronic pain management: a narrative review

Development and Validation of an Auricular Acupuncture Protocol for the Management of Chemotherapy-Induced Nausea and Vomiting in Cancer Patients

The diagnostic value of lncRNA HOTAIR for cervical carcinoma in vaginal discharge and serum

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