The Chemical Featuring, Toxicity, and Antimicrobial Activity of<i> Psidium cattleianum</i> (Myrtaceae) Leaves

Faleiro, José Henrique; Gonçalves, Randys Caldeira; Santos, Mara Núbia Guimarães dos; Silva, Diego Pereira da; Naves, Plínio Lázaro Faleiro; Malafaia, Guilherme

doi:10.1155/2016/7538613

Cited by 19 publications

(17 citation statements)

References 39 publications

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“…( Gupta, Chahal & Arora, 2011 ; Joseph & Priya, 2011 ). Antimicrobial activity has been described for several species such as Psidium cattleianum ( Faleiro et al, 2016 ) and Psidium guineense ( Fernandes et al, 2012 ).…”

Section: Introductionmentioning

confidence: 99%

Effect of seasonality on chemical profile and antifungal activity of essential oil isolated from leaves Psidium salutare (Kunth) O. Berg

Macêdo

Souza

Morais-Braga

et al. 2018

PeerJ

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Medicinal plants play a crucial role in the search for components that are capable of neutralizing the multiple mechanisms of fungal resistance. Psidium salutare (Kunth) O. Berg is a plant native to Brazil used as both food and traditional medicine to treat diseases and symptoms such as stomach ache and diarrhea, whose symptoms could be related to fungal infections from the genus Candida. The objective of this study was to investigate the influence of seasonal variability on the chemical composition of the Psidium salutare essential oil, its antifungal potential and its effect on the Candida albicans morphogenesis. The essential oils were collected in three different seasonal collection periods and isolated by the hydrodistillation process in a modified Clevenger apparatus with identification of the chemical composition determined by gas chromatography coupled to mass spectrometry (GC/MS). The antifungal assays were performed against Candida strains through the broth microdilution method to determine the minimum fungicidal concentration (MFC). Fungal growth was assessed by optical density reading and the Candida albicans dimorphic effect was evaluated by optical microscopy in microculture chambers. The chemical profile of the essential oils identified 40 substances in the different collection periods with γ-terpinene being the predominant constituent. The antifungal activity revealed an action against the C. albicans, C. krusei and C. tropicalis strains with an IC50 ranging from 345.5 to 2,754.2 µg/mL and a MFC higher than 1,024 µg/mL. When combined with essential oils at sub-inhibitory concentrations (MIC/16), fluconazole had its potentiated effect, i.e. a synergistic effect was observed in the combination of fluconazole with P.salutare oil against all Candida strains; however, for C. albicans, its effect was reinforced by the natural product in all the collection periods. The results show that the Psidium salutare oil affected the dimorphic transition capacity, significantly reducing the formation of hyphae and pseudohyphae in increasing concentrations. The results show that P. salutare oil exhibits a significant antifungal activity against three Candida species and that it can act in synergy with fluconazole. These results support the notion that this plant may have a potential use in pharmaceutical and preservative products.

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Section: Introductionmentioning

confidence: 99%

Effect of seasonality on chemical profile and antifungal activity of essential oil isolated from leaves Psidium salutare (Kunth) O. Berg

Macêdo

Souza

Morais-Braga

et al. 2018

PeerJ

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“…It is among the most exploited native fruits for its bioactive components with antioxidant potential (Pereira, 2018). The phytochemical analysis of the araç á crude ethanolic extract revealed the presence of compounds such as catechins, steroids, phenolic compounds, flavonoids and saponins (Faleiro et al, 2016). Pacheco (2015) demonstrated in his study that methanolic extracts of P. cattleyanum are effective in inhibiting the enzymes α-amylase and α-glycosidase in vitro and can be a promising candidate in the management of postprandial hyperglycemia.…”

Section: Myrtaceaementioning

confidence: 99%

Plants with Hypoglycemic Effect Cultivated in Medicinal Garden from Umuarama, Paraná-Brazil: A Review

Otênio

Oliveira

Baisch

et al. 2020

JAS

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The present study was carried out through a bibliographic survey of medicinal species, Asystasia gangetica, Catharanthus roseus, Arctium minus, Cynara scolymus, Anredera baselloides, Opuntia ficus-indica, Carica papaya, Ipomoea carnea, Ocimum gratissimum, Abelmoschus esculentus, Musa paradisiaca, Psidium cattleyanum, Syzygium cumini, Bougainvillea glabra, Bougainvillea spectabilis, Phyllanthus niruri, Capsicum baccatum var. pendulum and Zingiber officinale grown in the medicinal garden of Campus 2 of Universidade Paranaense, located in Umuarama, Paraná State, Brazil. The following databases were used for the bibliographic review: Scielo, Medline/Pubmed, and Google Scholar. All the species presented have hypoglycemic activity verified with preclinical and/or clinical pharmacological studies and have great potential for use in the treatment of diabetes or in combination with allopathic drugs. However, despite the pharmacological records found, additional scientific investigations are still needed to be able to use these species more safely and effectively.

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“…Red araçá pulp (RAP) has potential applications in the food and pharmaceutical industries, 4,5 wherein encapsulation technology is now widely implemented 6,7 . Encapsulation is required as most bioactive compounds in RAP are volatile or chemically unstable in the presence of oxygen, light, water, and heat 1,3,8–10 .…”

Section: Introductionmentioning

confidence: 99%

Red araçá pulp microencapsulation by hydrolyzed pinhão starch, and tara and arabic gums

et al. 2020

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BACKGROUND Red araçá is a Brazilian native species whose fruits are rich in phenolic acids, flavonoids, anthocyanins, and carotenoids. To preserve the properties of compounds during processing, red araçá pulp (RAP) was encapsulated by hydrolyzed pinhão starch (PS), tara gum (TG), and arabic gum (AG) in different blends in equal proportions, serving as a coating material. RESULTS Fresh RAP had a gallic acid equivalent of 3098 mg per 100 g of dry weight, 156.29 μg β‐carotene per gram of dry weight, total anthocyanins of 18 mg per 100 g of dry weight and exhibited high antioxidant activity. The highest encapsulation efficiency achieved with the PS, TG, and AG blend was 80.4% for the total carotenoids, and that for the total anthocyanins was 76% with the TG and AG blend. Only one step of antioxidant activity degradation was identified, and the carrier system PSTG was efficient at maintaining the antioxidant activity, with half‐life of 23.60–37.27 days. CONCLUSION The use of PS alone as a coating material or associated with TG and AG gums resulted in improved retention of bioactive compounds, these being an excellent alternative coating material since they improved the stability of the antioxidant activity of RAP. © 2020 Society of Chemical Industry

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The Chemical Featuring, Toxicity, and Antimicrobial Activity of Psidium cattleianum (Myrtaceae) Leaves

Cited by 19 publications

References 39 publications

Effect of seasonality on chemical profile and antifungal activity of essential oil isolated from leaves Psidium salutare (Kunth) O. Berg

Effect of seasonality on chemical profile and antifungal activity of essential oil isolated from leaves Psidium salutare (Kunth) O. Berg

Plants with Hypoglycemic Effect Cultivated in Medicinal Garden from Umuarama, Paraná-Brazil: A Review

Red araçá pulp microencapsulation by hydrolyzed pinhão starch, and tara and arabic gums

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