The Chemistry of Ethylene Oxide: I. An Analysis for Ethylene Oxide

Abstract

Accurate and convenient analyses for ethylene oxide can be obtained using 1% periodic acid in dilute perchloric acid as reagent. The time required is less than an hour and the precision is about 0.1–0.2%.

The Chemistry of Ethylene Oxide: V. The Reaction of Ethylene Oxide With Halide Ions in Neutral and Acid Solution

“…concentration was varied from about 2 to 10 times that of the oxide. The reaction mixture was then analyzed for halohydrin by acid-base titration or for glycol by periodate oxiclation, or both, using methocls very similar to those previously described (3). The analyses were carefully tested on synthetic mixtures of acid, glycol, and halohydrin before use.…”

Other Methods for Epoxide Determination

“…This sequence appears to have been first used by Eastham and Latremouille, (32) who carried out the hydrolysis and oxidation with aqueous periodic acid (preferably with perchloric acid present as catalyst for the hydrolysis), and then determined the amount of periodic acid which remained. Subsequent workers have preferred to estimate the amount of formaldehyde produced by the periodic acid oxidation of the ethylene glycol, using some colorimetrie means.…”

Ethylene Oxides

“…The resulting 1,2-diols are assayed by oxidative titration with periodic acid in aqueous sulfuric acid or perchloric acid. 475 Alternatively, carbonyl compounds formed on periodic acid oxidation of 1,2-diols may be determined colorimetrically with phenylhydrazine or other suitable reagents.2479 374 Addition of certain sulfur-containing nucleophiles constitutes the basis of several analytical procedures. Among these nucleophiles are sodium sulfite,1675 sodium thiosulfate,l491 and hydrogen sulfide.…”