The Chemistry of Large Molecules

The Effects of Injected Biotin and Dethiobiotin on Butter Yellow Carcinogenesis in Rats Fed a Protective Diet

“…However, du Vigneaud et al (1942) have reported that the daily addition of 2 p,g of crystalline biotin to such a diet destroys its protection. This finding was confirmed in more extensive experiments by Burk et al (1943), though Kline, Miller, and Rusch (1945) demonstrated that the dietary casein could be replaced by egg white and injections of 6 p,g of biotin weekly without affecting the protection.…”

Binders and Base Materials for Active Carbon - Function of Sugars, Coal Tar Pitch, Anthracite, and Cellulose

“…Oxygen in the ring means that, when this oxygen is driven out in carbonization, possibly dragging a carbon with it, at least two carbons are left behind with unsatisfied bonds. That there can be ring cleavage in the cellulose molecule without necessarily shortening the length of the chain was recently indicated by Ott (10), who stated that cellulose is "one of the most rigid high polymers known".…”

“…Distillation procedures have been studied by previous investigators to determine their merit in the purification of lactic acid. Distillation in a vacuum (10,26), steam distillation under reduced pressures (6,11,12,21,22), distillation in a stream of gas (14), and passage of superheated steam through condensation polymers of lactic acid (17) have been described as purification procedures. Since lactic acid of good quality is still relatively expensive (15), it appears that the distillation and other purification methods are not entirely satisfactory in their present stage of development and that improved purification procedures are needed.…”