The Chemistry of Mammalian Lipids

Stoffel, Wilhelm

doi:10.1007/978-3-642-87367-6_1

Cited by 4 publications

(3 citation statements)

References 247 publications

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“…The high content of mono-, di-and trienoic fatty acids is characteristic of cardiolipin, which constitutes an important component of mitochondrial lipids (Stoffel, 1967). Bovine and ovine sperm cardiolipins have a high percentage of oleic and linoleic acids (Neill & Masters, 1972 …”

Section: Discussionmentioning

confidence: 99%

Fatty acids and fatty aldehydes of buffalo seminal plasma and sperm lipid

Jain¹,

Anand²

1976

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Summary. Analysis of the fatty acids of total and neutral lipids, glycolipids, phospholipids and gangliosides of buffalo spermatozoa and seminal plasma showed that there were high levels of polyunsaturated acids. Neutral lipids were the richest in polyunsaturated acids (55 % in spermatozoa and 61 % in seminal plasma). The major saturated acid of all the principal classes was stearic acid and the major unsaturated acid was docosahexaenoic acid (22: 6\g=w\3)except in the neutral lipids in which it was arachidonic acid (20:4\g=w\6).The major aldehyde was palmitaldehyde (16:0) in buffalo sperm lipids and docosanal (22:0) in seminal plasma. More than 50% of the total aldehydes was contributed by aldehydes with a chain length greater than 18 carbon atoms.

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Section: Discussionmentioning

confidence: 99%

Fatty acids and fatty aldehydes of buffalo seminal plasma and sperm lipid

Jain¹,

Anand²

1976

Reproduction

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“…Das in der menschlichen Leber nach Vollkost aus 1-14C-Acetat synthetisierte Fetts~uregemisch (Abb. 3) ist typisch fiir die Fetts~ureneosynthese und Fetts~ureverl~ngerung [12,16,28]. Letztere driickt sich auch in der C~0--~ C22-Fettsi~ureaktivit~t aus, die 14% der Gesamtaktivit~t ausmachte.…”

Section: I S K U S S I O Nunclassified

Experimentelle Untersuchungen an menschlichen Leberpunktaten zum Lipidstoffwechsel aus 1-14C-Acetat und dessen Abhängigkeit vom Kohlenhydrat-Fett-Gehalt der Nahrung

1974

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“…This is further supported by the ortho-268 chromasia of the ganglion cells, as phosphatides are probably the principal lipid substances inducing metachromasia of lipid material (49). The blue colour by the Nile blue sulphate method of Cain on the other hand indicates acidic lipids, and gangliosides react acidically due to one or more N-acetyl-neuraminic acid residues (66). I t is probable that the positive PAPS-reaction indicating sialic acid (65) is due to those sialic acid residues of gangliosides and not to sialomucins as indicated in Table 4, but exact histochemical differentiation is not possible.…”

Section: B the Stored Materials In Mucopolysaccha-mentioning

confidence: 99%

Mucopolysaccharidosis Type Iii (Sanfilippo's Syndrome)

Jensen

1971

Acta Pathologica Microbiologica Scandinavica Section A Patholog

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In a clinically diagnosed case of Sanfilippo's syndrome (Mucopolysaccharidosis type III) histopathological examination of the eyes revealed accumulation of a granular material mainly in the sclera and to a lesser degree in the cornea and ciliary body. Similar scleral changes have previously been reported in various types of mucopolysaccharidosis in six cases only, and ciliary body changes in two cases only. It is emphasized that ocular involvement including corneal changes may be found histopathologically even if not clinically detected. The main histopathological findings in the cerebrum and cerebellum were ballooning of ganglion cells similar to the findings in other types of storage disease. By applying a battery of histochemical methods to the ocular and cerebral material, the findings indicated 1) a difference between the stored material in the brain and in the eyes, 2) that the stored material in the ganglion cells of the brain was probably of a ganglioside nature and 3) that the material in the eyes was consistent with an acid mucopolysaccharide, undoubtedly sul‐phated and probably rich in heparitin sulphate. These findings are compared with the suggested biochemical changes and the correlation between these and the morphology is discussed. The writer is in favour of the theory of a basic enzyme defect leading to accumulation of the granular material in the cells. Addition of normal and pathological cytoplasmic constituents are probably responsible for the difference in histochemical findings, especially in fibrocytes and ganglion cells, as revealed by the present study. The eyes have not previously been histopathologically or histochemically examined in Sanfilippo's syndrome.

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The Chemistry of Mammalian Lipids

Cited by 4 publications

References 247 publications

Fatty acids and fatty aldehydes of buffalo seminal plasma and sperm lipid

Fatty acids and fatty aldehydes of buffalo seminal plasma and sperm lipid

Experimentelle Untersuchungen an menschlichen Leberpunktaten zum Lipidstoffwechsel aus 1-14C-Acetat und dessen Abhängigkeit vom Kohlenhydrat-Fett-Gehalt der Nahrung

Mucopolysaccharidosis Type Iii (Sanfilippo's Syndrome)

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