1995
DOI: 10.1073/pnas.92.1.14
|View full text |Cite
|
Sign up to set email alerts
|

The chemistry of phyletic dominance.

Abstract: Studies of arthropod defensive chemistry continue to bring to light novel structures and unanticipated biosynthetic capabilities. Insect alkaloids, such as the heptacyclic acetogenin chilocorine and the azamacrolides, exemplify both of these aspects of arthropod chemistry. Spider venoms are proving to be rich sources of neuroactive components of potential medical interest. The venom of a fishing spider, Dolomedes okefinokensis, has yielded a polyamine which reversibly blocks L-and R-type voltage-sensitive calc… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1

Citation Types

0
23
0
4

Year Published

1997
1997
2012
2012

Publication Types

Select...
5
2

Relationship

0
7

Authors

Journals

citations
Cited by 50 publications
(27 citation statements)
references
References 20 publications
(16 reference statements)
0
23
0
4
Order By: Relevance
“…± Studies of arthropod defensive chemistries continue to bring to light novel structures and unanticipated biosynthetic capabilities [1]. In the last decade, insecticide toxins from arthropod venoms have been the subjects of considerable emphasis [2].…”
mentioning
confidence: 99%
See 1 more Smart Citation
“…± Studies of arthropod defensive chemistries continue to bring to light novel structures and unanticipated biosynthetic capabilities [1]. In the last decade, insecticide toxins from arthropod venoms have been the subjects of considerable emphasis [2].…”
mentioning
confidence: 99%
“…Toxicity assays demonstrated a potent lethal effect of the alkaloid toxin to the spider preys; topical applications of the tetrahydro-b-carboline at first caused clear signs of neurotoxicity, followed by the death of preys. The structure of the major component, a tetrahydro-b-carboline, among the alkaloid toxins was elucidated by means of UV spectrophotometry, ESI mass spectrometry, 1 H-NMR spectroscopy, and high-resolution mass spectrometry. The structure of the natural toxin was determined as 1-(2-guanidinoethyl)-1,2,3,4-tetrahydro-6-hydroxymethyl)-bcarboline; the investigation of the pharmacological properties and neurotoxic actions of this compound may be used in the future as reference for the development of new drugs to be applied at level of pest control in agriculture.…”
mentioning
confidence: 99%
“…Em meados da década de 90, Meinwald & Eisner (1995) bloqueia os receptores glutamatérgicos tipo RCAINATO. O mesmo grupo citou também que este composto seria eficaz na proteção contra a morte neuronial durante a isquemia (McCormic et al, 1999;Meinwald apud Friedlander, 1999).…”
Section: João Ricardo E João Apolinário -Primavera Nos Dentes -Secos unclassified
“…B: Acilpoliamina isolada da aranha Argiope lobata e denominada argiotoxina 636 (ArgTx-636, 636 Da) (Bateman et al,, 1985). C: Nucleosídeo sulfatado HF-7 (631 Da) (Meinwald & Eisner, 1995).…”
Section: João Ricardo E João Apolinário -Primavera Nos Dentes -Secos unclassified
“…Hymenopterans (including bees, wasps, and ants) are a highly prevalent and widespread group of insects that evolved more than 300 million years ago (Meinwald and Eisner, 1995). These insects are classified in two groups based on their life history: social and solitary.…”
Section: Insecticidal Peptides From Hymenopteran Venomsmentioning
confidence: 99%