The Child Behavior Checklist Dysregulation Profile in Preschool Children: A Broad Dysregulation Syndrome

Geeraerts, Sanne B.; Deutz, Marike H. F.; Deković, Maja; Bunte, Tessa; Schoemaker, Kim; Espy, Kimberly Andrews; Prinzie, Peter; Baar, Anneloes L. van; Matthys, Walter

doi:10.1016/j.jaac.2015.04.012

Cited by 59 publications

(78 citation statements)

References 31 publications

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“…Our results support conceptualizing dysregulation using a bi‐factor model, in which dysregulation represents a broad syndrome that is associated with but also independent from the affective, cognitive, and behavioral subdomains of dysregulation. This finding is largely consistent with theoretically based models that conceptualize dysregulation as a transdiagnostic construct underlying multiple psychiatric disorders in both NT and ASD populations [Duetz et al, ; Geeraerts et al, ; Weiss et al, ].…”

Section: Discussionsupporting

confidence: 85%

“…Finally, a bi‐factor model indicates that dysregulation is a broad, independent syndrome that directly influences symptoms even in the presence of each specific subdomain (Model 4). This model, which was previously supported in psychometric studies of the CBCL‐DP in children without ASD, suggests that dysregulation is an independent factor that, together with the subdomain factors, influences psychiatric symptoms [Duetz, Geeraerts, van Baar, Dekovic, & Prinzie, ; Geeraerts et al, ].…”

Section: Introductionmentioning

confidence: 59%

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Investigating the factor structure of the child behavior checklist dysregulation profile in children and adolescents with autism spectrum disorder

et al. 2019

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Dysregulation has been identified as an important risk factor for the development of psychiatric disorders in individuals with autism spectrum disorder (ASD). Therefore, it is necessary to empirically characterize dysregulation and identify psychometrically sound and readily available assessment methods in the ASD population. We sought to evaluate the factor structure of the Child Behavior Checklist‐Dysregulation Profile (CBCL‐DP), an established dysregulation measure in neurotypical children that is derived from the CBCL, in a large, clinically referred sample of children, ages 6–18 years, with ASD (n = 727). Confirmatory factor analysis was used to characterize dysregulation and assess the validity of the CBCL‐DP in children with ASD. Our findings support a bi‐factor model of dysregulation in which dysregulation is a broad and distinct syndrome that is associated with the three subdomains of the CBCL‐DP, anxiety/depression (AD), attention problems (AP), and aggressive behavior (AGG). Dysregulation was associated with most items in the AD and AGG domains and few items in the AP domain. This association with AD and AGG indicates that dysregulation in ASD may be conceptualized as the combined experience of internalized, negative mood states and externalized, reactive behaviors. These findings provide support as well as important caveats for the use of the CBCL‐DP as a measure of dysregulation in the ASD population. Autism Res 2020, 13: 436–443. © 2019 International Society for Autism Research, Wiley Periodicals, Inc. Lay Summary Dysregulation is a risk factor for psychiatric disorders in ASD. This study examined if the CBCL‐DP, an established measure of dysregulation in neurotypical children, can be used to assess dysregulation in children with ASD. Findings provide evidence that in ASD, dysregulation is a broad construct that exists alongside anxiety/depression, attention problems, and aggression. These findings indicate that the CBCL‐DP can be considered a valid measure of dysregulation in the ASD population and could be used in clinical settings.

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Section: Discussionsupporting

confidence: 85%

Section: Introductionmentioning

confidence: 59%

Investigating the factor structure of the child behavior checklist dysregulation profile in children and adolescents with autism spectrum disorder

et al. 2019

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“…To our knowledge, the only study that has examined the factor structure of the DP in preschoolers in this way was conducted in a predominantly clinically referred sample of children with externalizing problems (Geeraerts et al., ), although we note that several studies have examined the factor structure of psychopathology more broadly—beyond the DP per se—in community samples of preschoolers (e.g., Olino et al., ). Because predominantly clinically referred samples may be biased toward elevations across all of the CBCL subscales, it is important to also assess the factor structure of the DP in nonreferred preschoolers originally ascertained in infancy/early childhood, before psychopathology symptoms emerge.…”

Section: Introductionmentioning

confidence: 99%

“…A key question with critical implications for the conceptualization of childhood psychopathology is whether the DP constitutes a syndrome in its own right versus merely reflects comorbidity among the three subscales of which it is comprised (described in Geeraerts et al., ). This can be addressed by examining the factor structure of the DP.…”

Section: Introductionmentioning

confidence: 99%

“…This can be addressed by examining the factor structure of the DP. Two recent studies explicitly did this: one focusing on a sample of 247 predominantly clinically referred preschoolers aged 3.5–5.5 years (Geeraerts et al., ) and the other utilizing a community sample of 697 school‐age children and adolescents (Deutz et al., ). Both found that a bifactor model—in which the items comprising these three CBCL subscales load both on their respective subscales as well as on a general ‘DP factor’—best described the structure of the DP compared to one‐factor (all items load on a single general factor) or second‐order (all items load on their respective factors, which load on a general factor) models (Deutz et al., ; Geeraerts et al., ).…”

Section: Introductionmentioning

confidence: 99%

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The dysregulation profile in preschoolers with and without a family history of autism spectrum disorder

Miller

Iosif

Young

et al. 2018

Child Psychology Psychiatry

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Background The ‘dysregulation profile’ (DP) is a measure of emotional and behavioral dysregulation that may cut across diagnostic boundaries. Siblings of children with autism spectrum disorder (ASD) who do not develop ASD themselves are at risk for atypical outcomes including behavioral challenges and therefore may be a useful population in which to investigate the structure of the DP in preschoolers. Methods We sought to examine the factor structure and predictors of the DP in a sample enriched for a wide range of phenotypic variation—36‐month‐olds with and without family histories of ASD—and to determine whether children with genetic liability for ASD are at risk for a phenotype characterized by elevated dysregulation. Data were collected from 415 children with (n = 253) and without (n = 162) an older sibling with ASD, all without ASD themselves, at 18, 24, and 36 months of age. Results Our findings replicate prior reports, conducted in predominantly clinically referred and older samples, supporting the superiority of a bifactor model of the DP in the preschool period compared to the second‐order and one‐factor models. Examiner ratings were longitudinally and concurrently associated with the DP at 36 months of age. Family history of ASD was associated with higher dysregulation in the Anxious/Depressed dimension. Conclusions These findings support the relevance of examining the structure of psychopathology in preschoolers and suggest that examiner observations as early as 18 months of age, particularly of overactivity, may help identify risk for later DP‐related concerns. Non‐ASD preschoolers with family histories of ASD may be at risk for a phenotype characterized by elevated dysregulation particularly in the Anxious/Depressed dimension by age 3.

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The wide‐ranging life outcome correlates of a general psychopathology factor in adolescent psychopathology

Laceulle

Chung

Vollebergh

et al. 2019

Personality & Mental Health

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Background The structure of psychopathology has been much debated within the research literature. This study extends previous work by providing comparisons of the links between psychopathology and several life outcomes (temperamental, economic, social, psychological and health) using a three‐correlated‐factors model, a bifactor model, a revised‐bifactor model and a higher‐order model. Methods Data from a sample of Dutch adolescents were used (n = 2 230), and psychopathology factors were modelled using self‐reported and parent‐reported longitudinal data from youth across four assessments during adolescence, from ages 11 to 19. Outcome variables were assessed at age 22 using adolescent‐reports and parent‐reports and more objective measures (e.g. body mass index). Results While no measurement model was clearly superior, we found modest associations between the psychopathology factors and life outcomes. Importantly, after taking into account a general factor, the associations with life outcomes decreased for the residual parts of thought problems (across all domains) and internalizing problems (for temperamental and psychological outcomes), but not for externalizing problems, compared with the traditional three‐correlated‐factors model. Patterns were similar for adolescent‐reported and parent‐reported data. Conclusions Findings suggest that a general factor is related to psychopathology and life outcomes in a meaningful way. Results are discussed in terms of individual differences in propensity to psychopathology and more broadly in light of recent developments concerning the structure of psychopathology. © 2019 The Authors Personality and Mental Health Published by John Wiley & Sons Ltd

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The Child Behavior Checklist Dysregulation Profile in Preschool Children: A Broad Dysregulation Syndrome

Cited by 59 publications

References 31 publications

Investigating the factor structure of the child behavior checklist dysregulation profile in children and adolescents with autism spectrum disorder

Investigating the factor structure of the child behavior checklist dysregulation profile in children and adolescents with autism spectrum disorder

The dysregulation profile in preschoolers with and without a family history of autism spectrum disorder

The wide‐ranging life outcome correlates of a general psychopathology factor in adolescent psychopathology

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