The Children's Affective Lability Scale: A psychometric evaluation of reliability

Gerson, Arlene C.; Gerring, Joan P.; Freund, Lisa S.; Joshi, Paramjit T.; Capozzoli, Joseph A.; Brady, Kathy; Denckla, Martha B.

doi:10.1016/s0165-1781(96)02851-x

Cited by 101 publications

(74 citation statements)

References 23 publications

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“…Emotional Dysregulation-As seen in Figure 4, total Children's Affective Lability Scale scores decreased significantly (paired t = 3.0, p = .02, d = 0.3) from mean pretreatment values comparable to those reported among inpatient samples, to posttreatment values below those reported for outpatient samples (see Gerson et al, 1996).…”

Section: Treatment Responsementioning

confidence: 83%

“…Similarly, at intake, four participants endorsed a history of nonsuicidal self-injurious behavior. Decreases in nonsuicidal self-injury on the K-SADS-DRS (item 30) were not statistically significant (paired t = 2.1, p = .06, d = 0.8), but it is noteworthy that no nonsuicidal self-injurious acts were reported during the final study assessment period.Emotional Dysregulation-As seen in Figure 4, total Children's Affective Lability Scale scores decreased significantly (paired t = 3.0, p = .02, d = 0.3) from mean pretreatment values comparable to those reported among inpatient samples, to posttreatment values below those reported for outpatient samples (see Gerson et al, 1996).Mood Symptoms-Adolescents showed significant improvement in depressive symptomatology. Total K-SADS-DRS summary scores dropped from the moderate range at intake (mean 23.1 ± 12.0) to the mild range at 12-month follow-up (mean 14.9 ± 10.6; paired t = 2.6, p = .03, d = .7).…”

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confidence: 85%

“…Emotional Dysregulation-Parents completed the Children's Affective Lability Scale (Gerson et al, 1996) designed to measure behavior reflective of emotional dysregulation. Items are rated on a 4-point scale indicating frequency of each behavior.…”

Section: Suicidality-suicidality Was Assessed Via the Mssi (mentioning

confidence: 99%

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Dialectical Behavior Therapy for Adolescents With Bipolar Disorder: A 1-Year Open Trial

Goldstein

Axelson

Birmaher

et al. 2007

Journal of the American Academy of Child & Adolescent Psych

225

138

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Objective-To describe an adapted version of dialectical behavior therapy for adolescents with bipolar disorder.Method-The dialectical behavior therapy intervention is delivered over 1 year and consists of two modalities: family skills training (conducted with individual family units) and individual therapy. The acute treatment period (6 months) includes 24 weekly sessions; sessions alternate between the two treatment modalities. Continuation treatment consists of 12 additional sessions tapering in frequency through 1 year. We conducted an open pilot trial of the treatment, designed as an adjunct to pharmacological management, to establish feasibility and acceptability of the treatment for this population. Participants included 10 patients (mean age 15.8 ± 1.5 years, range 14-18) receiving treatment in an outpatient pediatric bipolar specialty clinic. Symptom severity and functioning were assessed quarterly by an independent evaluator. Consumer satisfaction was also assessed posttreatment.Results-Feasibility and acceptability of the intervention were high, with 9 of 10 patients completing treatment, 90% of scheduled sessions attended, and high treatment satisfaction ratings. Patients exhibited significant improvement from pre-to posttreatment in suicidality, nonsuicidal selfinjurious behavior, emotional dysregulation, and depressive symptoms.Conclusions-Dialectical behavior therapy may offer promise as an approach to the psychosocial treatment of adolescent bipolar disorder. Keywords bipolar disorder; therapy; psychosocial treatmentOver the past decade, bipolar disorder (BP) in children and adolescents has gained increasing attention. Research suggests that BP affects approximately 1% of community adolescents (Lewinsohn et al., 1995), with estimates as high as 6% to 15% in clinical samples (Biederman et al., 1995;Pavuluri et al., 2006). Adolescents with BP exhibit a difficult illness course characterized by prolonged episodes, substantial inter-episodic symptoms, and marked functional impairment . High rates of psychosis, comorbidity, and hospitalizations have also been reported in this population . BP onset in adolescence is particularly pernicious due to its associations with drug and alcohol abuse, unprotected sex, and suicide (Brent and Lerner, 1994;Goldstein et al., 2005;McClellan et al., 1993). Evidence suggests the majority of adolescent-onset BP patients experience aCorrespondence to Dr. Tina R. Goldstein, Western Psychiatric Institute and Clinic, 100 North Bellefield Avenue, #463, Pittsburgh, PA 15213; goldsteintr@upmc.edu. Disclosure: The authors have no financial relationships to disclose. NIH Public Access NIH-PA Author ManuscriptNIH-PA Author Manuscript NIH-PA Author Manuscript deteriorating course into adulthood, with poor outcomes including chronic functional impairment and treatment resistance (Strober et al., 1995). Given the projected continuity and morbidity associated with adolescent BP, effective early intervention may minimize the longterm debilitating effects of the illness.Althoug...

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Section: Treatment Responsementioning

confidence: 83%

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confidence: 85%

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Dialectical Behavior Therapy for Adolescents With Bipolar Disorder: A 1-Year Open Trial

Goldstein

Axelson

Birmaher

et al. 2007

Journal of the American Academy of Child & Adolescent Psych

225

138

View full text Add to dashboard Cite

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“…IQ was measured using the Weschler Abbreviated Scale of Intelligence (Wechsler, 1999). Additionally, parents/guardians of youth participants completed the PGBI-10 M [Parent Version, General Behavior Inventory (Youngstrom et al, 2008), to assess the severity of behavioral and emotional dysregulation in their offspring during the last 6 months; only parents of BO and NBO completed this questionnaire]; the SCARED-P (Self-Report for Childhood Anxiety Related Emotional Disorders, Parent Version, to assess offspring anxiety over last 2 weeks; Birmaher et al, 1997); the CALS-P (The Children's Affective Lability Scale, Parent Version; Gerson et al, 1996); the MFQ-P (Mood and Feelings Questionnaire, Parent Version, to assess the severity of depression during the last 2 weeks; Angold et al, 1995); and a questionnaire to assess sociodemographic status represented by parental education (Hollingshead, 1975). Youth participants completed child report versions of affective symptomatology scales: the CALS-C, SCARED-C, MFQ-C. Pubertal status of youth was assessed using a self-report questionnaire (Petersen et al, 1988).…”

Section: Assessment Proceduresmentioning

confidence: 99%

Altered amygdala-prefrontal response to facial emotion in offspring of parents with bipolar disorder

Manelis

Ladouceur

Graur

et al. 2015

Brain

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This study aimed to identify neuroimaging measures associated with risk for, or protection against, bipolar disorder by comparing youth offspring of parents with bipolar disorder versus youth offspring of non-bipolar parents versus offspring of healthy parents in (i) the magnitude of activation within emotional face processing circuitry; and (ii) functional connectivity between this circuitry and frontal emotion regulation regions. The study was conducted at the University of Pittsburgh Medical Centre. Participants included 29 offspring of parents with bipolar disorder (mean age = 13.8 years; 14 females), 29 offspring of non-bipolar parents (mean age = 13.8 years; 12 females) and 23 healthy controls (mean age = 13.7 years; 11 females). Participants were scanned during implicit processing of emerging happy, sad, fearful and angry faces and shapes. The activation analyses revealed greater right amygdala activation to emotional faces versus shapes in offspring of parents with bipolar disorder and offspring of non-bipolar parents than healthy controls. Given that abnormally increased amygdala activation during emotion processing characterized offspring of both patient groups, and that abnormally increased amygdala activation has often been reported in individuals with already developed bipolar disorder and those with major depressive disorder, these neuroimaging findings may represent markers of increased risk for affective disorders in general. The analysis of psychophysiological interaction revealed that offspring of parents with bipolar disorder showed significantly more negative right amygdala-anterior cingulate cortex functional connectivity to emotional faces versus shapes, but significantly more positive right amygdala-left ventrolateral prefrontal cortex functional connectivity to happy faces (all P-values corrected for multiple tests) than offspring of non-bipolar parents and healthy controls. Taken together with findings of increased amygdala-ventrolateral prefrontal cortex functional connectivity, and decreased amygdala-anterior cingulate cortex functional connectivity previously shown in individuals with bipolar disorder, these connectivity patterns in offspring of parents with bipolar disorder may be risk markers for, rather than markers conferring protection against, bipolar disorder in youth. The patterns of activation and functional connectivity remained unchanged after removing medicated participants and those with current psychopathology from analyses. This is the first study to demonstrate that abnormal functional connectivity patterns within face emotion processing circuitry distinguish offspring of parents with bipolar disorder from those of non-bipolar parents and healthy controls.

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“…Although there is overlap among these constructs, studies have found that temperament and behavioral problem measures have at least some independence (Eisenberg et al, 1996(Eisenberg et al, , 2001Gerson et al, 1996;Maedgen & Carlson, 2000;Shields & Cicchetti, 2001). In terms of method and informant, some instruments involve observations or outcomes of child performance tasks (e.g., puzzle tasks).…”

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confidence: 99%

Internalizing Symptoms and Affective Reactivity in Relation to the Severity of Aggression in Clinically Referred, Behavior-Disordered Children

et al. 2007

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We examined the affective correlates of aggression in children referred to a partial hospitalization program for the treatment of behavior disorders who did not have a mood or anxiety disorder. Parent and teacher ratings of the children's impulsivity, internalizing symptoms, affective reactivity, and aggression were examined for their interrelationships and then entered into regression analyses to predict the child's level of aggression in the home, at school, and in the treatment program. Intercorrelations among three affective reactivity factors were modest. Both internalizing symptoms and affective reactivity contributed to aggression severity beyond impulsivity and demographics. Only child irritability predicted treatment program aggression. Because of their potential role in understanding children's behavioral disturbances, internalizing symptoms and negative emotionality merit careful assessment and treatment in treatment programs serving hard-to-manage children with behavior disorders.

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The Children's Affective Lability Scale: A psychometric evaluation of reliability

Cited by 101 publications

References 23 publications

Dialectical Behavior Therapy for Adolescents With Bipolar Disorder: A 1-Year Open Trial

Dialectical Behavior Therapy for Adolescents With Bipolar Disorder: A 1-Year Open Trial

Altered amygdala-prefrontal response to facial emotion in offspring of parents with bipolar disorder

Internalizing Symptoms and Affective Reactivity in Relation to the Severity of Aggression in Clinically Referred, Behavior-Disordered Children

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