The Circulatory Effects of Isoproterenol, Acetylstrophanthidin, and Volume Loading in Acute Pericardial Tamponade

Treister, Bernard; Gianelly, Ralph E.; Cohn, Keith; Harrison, Donald C.

doi:10.1093/cvr/3.3.299

Cited by 26 publications

(7 citation statements)

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“…When definitive pericardiocentesis or surgery is not immediately available, intravascular volume expansion has been advocated as an effective supportive measure (11,24,25) on the basis of experimental (9,13,16,26) and clinical (3,6) evidence. However, in recent experimental and clinical studies intravascular volume expansion during tamponade did not result in an increase in cardiac output or stroke volume (18).…”

Section: Introductionmentioning

confidence: 99%

Cardiac tamponade in dogs with normal coronary arteries. I. Effect of changing intravascular volume on hemodynamics and myocardial blood flow

et al. 1984

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Intravascular volume expansion has been shown to improve cardiac output in experimental cardiac tamponade. To determine the limitations of intravascular volume manipulation, acute tamponade was created in 20 anesthetized, spontaneously breathing dogs. The intrapericardial volume causing tamponade was determined for each animal, and kept constant. Hemodynamics were recorded with and without tamponade at multiple levels of intravascular volume. During cardiac tamponade, intravascular volume expansion increased cardiac output only in animals which were initially volume-depleted. Volume expansion of normovolemic or hypervolemic animals caused minimal changes in cardiac output, but increased atrial and aortic pressures. Intravascular volume depletion of the normovolemic animal caused a significant decline in cardiac output, in contrast to the trend towards an increased output following phlebotomy of the volume-expanded animals. In general, the benefit of intravascular volume expansion during cardiac tamponade could only be demonstrated when atrial pressures were below 12 mm Hg.

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Section: Introductionmentioning

confidence: 99%

Cardiac tamponade in dogs with normal coronary arteries. I. Effect of changing intravascular volume on hemodynamics and myocardial blood flow

et al. 1984

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“…The rationale for a volume resuscitation lies on the correction of a patent or latent hypovolemia, in order to treat or delay a right ventricle diastolic collapse, responsible for the hemodynamic instability [25]. The aim is also to maintain an accep- Few data from old animal studies [26,27] and small numbers of patients [28] show some controversial results. In a recent work, Sagristà-Sauleda et al [29] studied on 49 patients with cardiac tamponade the effect of a fluid loading with 500 ml of saline over 10 min.…”

Section: Volume Resuscitationmentioning

confidence: 99%

Cardiac tamponade

Bodson

Bouferrache

Vieillard‐Baron

2011

Current Opinion in Critical Care

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“…A decrease in cardiac performance in the late stages of tamponade is accompanied by bradycardia and hypotension (3,4) which has been shown to be partially due to a vagally mediated depressor reflex (5). Studies during acute tamponade using a-and /3-blockade have demonstrated that the sympathetics maintain cardiac performance by augmenting the contractile state of the myocardium (6,18). Although indirect evidence exists for the acti vation o f the autonomic neurons' system during cardiac tamponade, electrophysiological recordings of changes in autonomic afferent and efferent nerve activity have not been made during cardiac tamponade.…”

Section: Introductionmentioning

confidence: 99%

Changes in Autonomic Nerve Activity during Acute Pericardial Tamponade

Castañer¹,

Kostreva²,

Kampine³

1980

Cardiology

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Acute experimental pericardial tamponade in anesthetized mongrel dogs produces marked alterations of autonomic reflex mechanisms. Afferent nerve activity from left ventricular receptors is inhibited during tamponade, whereas pericardial receptors are excited. Sympathetic efferent nerve activity traversing the ansae subclaviae is markedly increased during tamponade by the carotid sinus baroreceptor reflex and also by other undefined mechanisms. The increase in sympathetic activity produces a transient tachycardia and inotropic effect. A paradoxical increase in cardiac vagal efferent nerve activity occurs during the period of maximal hypotension and appears to override the normal baroreceptor reflexes. This increase in vagal efferent activity corresponds to the development of a marked bradycardia during prolonged cardiac tamponade.

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The Circulatory Effects of Isoproterenol, Acetylstrophanthidin, and Volume Loading in Acute Pericardial Tamponade

Cited by 26 publications

References 0 publications

Cardiac tamponade in dogs with normal coronary arteries. I. Effect of changing intravascular volume on hemodynamics and myocardial blood flow

Cardiac tamponade in dogs with normal coronary arteries. I. Effect of changing intravascular volume on hemodynamics and myocardial blood flow

Cardiac tamponade

Changes in Autonomic Nerve Activity during Acute Pericardial Tamponade

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