“…Such a complex muscular architecture, not present in the smooth left atrium, has recently raised new interest among electrophysiologists as a potential electric barrier and arrhythmia focus. 23,24 Third, the RAA has lower plasticity, and it lacks significant remodeling in AF, as demonstrated by Subramanian et al, 16 who studied appendage enlargement in AF and found that LAA area increased significantly (6.4 vs 4.3 cm 2 ), whereas RAA area did not (5.7 cm 2 in AF vs 5.4 cm 2 in sinus rhythm). We can assume that the different muscular architecture and structure may prevent RAA dilatation and THR formation, but these data need further investigation.…”