The clinical and economic impact of the use of diabetes-specific enteral formula on ICU patients with type 2 diabetes

Han, Yin-Yi; Lai, Sheng-Ru; Partridge, Jamie; Wang, Michael Y.; Sulo, Suela; Tsao, F.-W.; Hegazi, Refaat

doi:10.1016/j.clnu.2016.09.027

Cited by 13 publications

(6 citation statements)

References 28 publications

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“…Excessive glucose based energy provision is associated with hyperglycemia, enhanced CO 2 production, enhanced lipogenesis, increased insulin requirements and no advantage in protein sparing in comparison with a lipid based energy provision [114]. The use of diabeticspecific enteral formula in ICU patients suffering from Type 2 Diabetes Mellitus seems to improve the glucose profile [188,189] and may have clinical and economic impact [188]. The hyperglycemia related to PN enriched in dextrose requires higher doses of insulin [190].…”

Section: Commentary To Recommendations 23 -25mentioning

confidence: 99%

ESPEN guideline on clinical nutrition in the intensive care unit

et al. 2019

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s u m m a r yFollowing the new ESPEN Standard Operating Procedures, the previous guidelines to provide best medical nutritional therapy to critically ill patients have been updated. These guidelines define who are the patients at risk, how to assess nutritional status of an ICU patient, how to define the amount of energy to provide, the route to choose and how to adapt according to various clinical conditions. When to start and how to progress in the administration of adequate provision of nutrients is also described. The best determination of amount and nature of carbohydrates, fat and protein are suggested. Special attention is given to glutamine and omega-3 fatty acids. Particular conditions frequently observed in intensive care such as patients with dysphagia, frail patients, multiple trauma patients, abdominal surgery, sepsis, and obesity are discussed to guide the practitioner toward the best evidence based therapy. Monitoring of this nutritional therapy is discussed in a separate document.

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Section: Commentary To Recommendations 23 -25mentioning

confidence: 99%

ESPEN guideline on clinical nutrition in the intensive care unit

et al. 2019

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“…Previous studies showed an effect on acquired infections . In 961 Taiwanese critically ill patients, LCF was associated with a 2‐day shorter length of stay and significant lower mortality rates, as well as ICU costs, but this was a retrospective study and included only patients with type 2 diabetes . In our study, the incidence of ventilator‐associated pneumonia was very low (due to the use of SDD) and was equal across groups.…”

Section: Discussionmentioning

confidence: 69%

Glycemic Effects of a Low‐Carbohydrate Enteral Formula Compared With an Enteral Formula of Standard Composition in Critically Ill Patients: An Open‐Label Randomized Controlled Clinical Trial

Steen

Rijkenberg

Sechterberger

et al. 2017

J Parenter Enteral Nutr

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“…Guidelines for the Early Management of Patients with Acute Ischemic Stroke recommends blood glucose levels ranging from 7.8 to 10 mmol/L . Although aggressively tested and treated, hyperglycemia has been a common and tough problem in critically ill patients generally and especially in severe acute ischemic stroke patients . We believe that the following factors might be the reasons for hyperglycemia: (1) Stress may be one of the main causes of hyperglycemia.…”

Section: Discussionmentioning

confidence: 99%

“…10 Although aggressively tested and treated, hyperglycemia has been a common and tough problem in critically ill patients generally and especially in severe acute ischemic stroke patients. 12 We believe that the following factors might be the reasons for hyperglycemia:…”

Section: Discussionmentioning

confidence: 99%