The Clinical Application of Prostaglandin E<sub>1</sub> on Orthodontic Tooth Movement - A Clinical Trial

Patil, Anand; Keluskar, K M; Gaitonde, S. D.

doi:10.1177/0974909820050204

Cited by 23 publications

(20 citation statements)

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“…Corticosteroid hormones, vitamin D3, parathyroid hormone, and thyroxin have all been shown to increase tooth movement in animal studies . In human trials investigating the application of prostaglandins on tooth movement, the results have suggested a possible acceleration . Therefore, drugs blocking their action, such as aspirin and NSAID's could slow orthodontic tooth movement as demonstrated in additional animal studies .…”

Section: Non‐surgical Methodsmentioning

confidence: 96%

Accelerated orthodontic treatment ‐ what's the evidence?

Miles

2017

Australian Dental Journal

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The demand and accessibility of orthodontic care has increased but has also been accompanied by patient requests for shorter treatment times. Longer orthodontic treatment increases the risk of decalcification, gingival recession, and root resorption and so shorter treatment times have multiple advantages as well as appealing to patient's desires. Numerous techniques and materials have been suggested to reduce treatment times but, in most cases, are based upon selected case reports with no prospective clinical trials to validate claims. The present review examines many of the current options purported to accelerate orthodontic tooth movement and the level of evidence presently available. There is some evidence to suggest that low-level laser therapy and a corticotomy involving the raising of a muco-periosteal flap are associated with accelerated orthodontic tooth movement; however, the current level of evidence is low to moderate in quality. For this reason, further research is required before routine application could be recommended.

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Section: Non‐surgical Methodsmentioning

confidence: 96%

Accelerated orthodontic treatment ‐ what's the evidence?

Miles

2017

Australian Dental Journal

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“…Another prostaglandin that has been reported to speed up orthodontic tooth movement is Prostaglandin E 1 (PGE 1 ). Prostaglandin E 1 (PGE 1 ) has also been seen to be induced by mechanical stress and cause bone remodelling, Patil and his co-workers had shown that even minimal amounts of PGE 1 injection had significant increase in tooth movement [9]. Due to the hyperalgesia that accompanies with the local injection of PGE 1, an analogue of it which is misoprostol was tried out.…”

Section: Pharmacological Methodsmentioning

confidence: 99%

Accelerated Orthodontics

Patil¹,

Maan²

2019

Current Approaches in Orthodontics

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Clinical orthodontics is ever dynamic branch of Dentistry. Traditionally orthodontics was always considered as aesthetic treatment of face & also needed for proper oral oral function. This treatment may take up 2-3 years of total duration. The chapter describes changing trends in this aspect wherein we speed up the treatment by various methods thus reducing the overall time duration. These modalities include alteration in bio mechanics, pharmacological, chemical & by biological means. It is also cautioned here that the clinician has to take up these changing trends based on sound clinical knowledge & evidence based applicability.

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“…[40] and Anand et al . [44] demonstrated increased rate of orthodontic tooth movement with exogenous injections of PGE2 [Figures 2 and 3]. Studies indicate that Prostaglandins increase the number of osteoclasts as well as stimulate osteoblastic cell differentiation and new bone formation.…”

Section: Role Of Prostaglandins In Mediating Otmmentioning

confidence: 99%

Understanding the advances in biology of orthodontic tooth movement for improved ortho-perio interdisciplinary approach

Patil

Shetty

Setty

et al. 2013

J Indian Soc Periodontol

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This article provides an insight on detailed current advances in molecular understandings of periodontal ligament cells and the influence of orthodontic force on them in the light of recent advances in molecular and genetic sciences. It sequentially unfolds the cellular events beginning from the mechanical force initiated events of cellular responses to bone remodeling. It also highlights the risks and limitations of orthodontic treatment in certain periodontal conditions, the important areas of team work, orthodontic expectations from periodontal treatment and the possibility of much more future combined research to improve the best possible periodontal health and esthetic outcome of the patient.

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The Clinical Application of Prostaglandin E₁ on Orthodontic Tooth Movement - A Clinical Trial

Cited by 23 publications

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Accelerated orthodontic treatment ‐ what's the evidence?

Accelerated orthodontic treatment ‐ what's the evidence?

Accelerated Orthodontics

Understanding the advances in biology of orthodontic tooth movement for improved ortho-perio interdisciplinary approach

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The Clinical Application of Prostaglandin E1 on Orthodontic Tooth Movement - A Clinical Trial

Cited by 23 publications

References 0 publications

Accelerated orthodontic treatment ‐ what's the evidence?

Accelerated orthodontic treatment ‐ what's the evidence?

Accelerated Orthodontics

Understanding the advances in biology of orthodontic tooth movement for improved ortho-perio interdisciplinary approach

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Product

Resources

About

The Clinical Application of Prostaglandin E₁ on Orthodontic Tooth Movement - A Clinical Trial