The Clinical Effect of Zoledronic Acid Combined with Teriparatide in Perverting Recurrent Fracture of Osteoporotic Vertebral Compressive Fractures in the Elderly after Percutaneous Kyphoplasty

Zhao, Ling; Yang, Xinming; Zhang, Ying

doi:10.4236/ss.2021.126018

Cited by 1 publication

(1 citation statement)

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“…In China, osteoporotic patients account for 15% of the population over the age of 50, of which 1 / 3 are accompanied by vertebral fracture, and the risk of vertebral fracture increases with age [13,14]. OVCF is a spinal fracture induced by systemicabnormal bone metabolism, decreased bone mass and increased bone fragility [15]. Pathologically, the vertebral body collapses and the height decreases, which affects the stability of the spine and is prone to kyphosis, resulting in the patient's shortening and hunchback deformity, affecting daily life [16].…”

Section: Discussionmentioning

confidence: 99%

Treatment of osteoporotic vertebral compression fracture by precise injection and staged perfusion of bone cement kyphoplasty: a comparison study

Huang

Zhou

et al. 2022

Preprint

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Study design: Retrospective cohort study.Objective: To explore the clinical effect of precise injection and staged perfusion of bone cement kyphoplasty in the treatment of osteoporotic vertebral compression fracture.Methods: 110 patients treated with kyphoplasty from January 2020 to June 2021 were selected and divided into experimental group (n = 55) and control group (n = 55) according to different surgical methods. The experimental group was treated with precise injection and staged perfusion of bone cement kyphoplasty, while the control group was treated with traditional kyphoplasty. The operation time,intraoperative blood loss and amount of bone cement injection were recorded. The pain improvement was evaluated by VAS score. The operation effect were evaluated by anterior height of injured vertebral body, middle height of injured vertebral body, wedge angle of injured vertebral body and distribution grade of bone cement. The incidence of surgical complications was evaluated by the number of bone cement leakage.Results: There were no significant difference in the operation time, intraoperative blood loss and the amount of bone cement injection in two groups. There were no significant difference in VAS scores at 2h, 4h and 48h after operation between the two groups (P > 0.05); There were no significant difference in the ratio of anterior height of injured vertebral body between the two groups on the third day after operation and the last follow-up (P > 0.05); There were no significant difference in the ratio of middle height of injured vertebral body between the two groups on the third day after operation and the last follow-up (P > 0.05); There were no significant difference in wedge angle of injured vertebral body between the two groups at the third day after operation and the last follow-up (P > 0.05). There was significant difference in the distribution grade of bone cement between the two groups (P < 0.01); There was significant difference in the number of bone cement leakage between the two groups (P < 0.01), In cases of bone cement leakage, there were 1 case of type C, 1 case of type S in the experimental group, 7 cases of type C and 2 cases of type S in the control group.Conclusion: Precise injection and staged perfusion of bone cement kyphoplasty in the treatment of osteoporotic vertebral compression fracture can effectively reduce surgical complications and improve surgical efficacy.

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Section: Discussionmentioning

confidence: 99%