The clinical efficacy and efficiency of a 100‐IU starting dose of recombinant follicle stimulating hormone (Puregon^®) in Korean women undergoing in vitro fertilization and embryo transfer

Abstract

The starting dose of 100 IU rhFSH has a good safety profile, and is adequate in controlled ovarian hyperstimulation for IVF with a small amount of gonadotropin administered.

Mild IVF using GnRH agonist long protocol is possible: Comparing stimulations with 100 IU vs. 150 IU recombinant FSH as starting dose

“…Devroey et al [20] in a study with 51 patients, obtained a mean of 11.7 oocytes with a total dose of 1,807 IU of rFSH given over 13.3 days; and Moon et al [21] in a study with 40 patients, obtained 8.4 oocytes with a total dose of 1,480 IU rFSH given over 10.8 days.…”

Clinical efficacy of the gonadotropin‐releasing hormone antagonist, ganirelix, in Korean women undergoing controlled ovarian hyperstimulation for in vitro fertilization and embryo transfer with recombinant follicle‐stimulating hormone

“…Approximately 36 h after hCG was given, oocyte retrieval was carried out followed by IVF or ICSI. The ICSI was carried out according to conventional protocol 8 . No more than three embryos were to be transferred on 2–5 days after oocyte retrieval.…”

“…The ICSI was carried out according to conventional protocol. 8 No more than three embryos were to be transferred on 2-5 days after oocyte retrieval. Progesterone in oil (Progest, Samil, Korea) at a rate of 50 mg intramuscular (i.m.)…”