The Clinical Efficacy of Silicone Punctal Plug Therapy

Tai, Ming‐Cheng; Cosar, C; Cohen, Elisabeth J.; Rapuano, Christopher J.; Laibson, Peter R.

doi:10.1097/00003226-200203000-00001

Cited by 136 publications

(84 citation statements)

References 16 publications

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“…The function of the lens is to provide a fluid cushion for the cornea and protect it from the rubbing effects of the lids [38,39,40]. Some authors have noticed an improvement in the cornea through the use of temporary silicone plugs to help increase tear volume [41]. …”

Section: Treatmentmentioning

confidence: 99%

Neurotrophic Keratitis

et al. 2013

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Neurotrophic keratitis (NK) is a rare degenerative corneal disease that occurs as a result of partial or total impairment of trigeminal innervations, leading to a reduction (hypoesthesia) in or loss (anaesthesia) of corneal sensitivity. The impairment of sensory innervation causes a reduction in the lacrimation reflex and the vitality, metabolism and mitosis of epithelial cells, with subsequent deficiency in epithelial repair, stromal and intracellular oedema, loss of microvilli, and abnormal development of the basal lamina. Several recent studies have proposed different therapies based on different aetiopathogenetic theories. The aim of the therapy is to treat aetiopathogenesis and, at the same time, promote corneal healing. In this paper, we report the aetiology, diagnosis, management, and medical and surgical treatment of NK, also indicating future treatments based on the most recent studies.

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Section: Treatmentmentioning

confidence: 99%

Neurotrophic Keratitis

et al. 2013

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“…Consistent with our results, previous studies have shown that spontaneous plug loss is the most common problem with punctal plugs, occurring in 30 --50%. 9,10 Other known possible complications of punctal occlusion include pruritus, discomfort, lesions of the conjunctiva and cornea, epiphora, canaliculitis and pyogenic granuloma. 11 None of the aforementioned was observed in our study.…”

Section: Discussionmentioning

confidence: 99%

Punctal occlusion is safe and efficient for the treatment of keratoconjunctivitis sicca in patients with ocular GvHD

Sabti

Halter

Fränkl

et al. 2011

Bone Marrow Transplant

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The use of punctal plugs in the treatment of keratoconjunctivitis sicca (KCS) in inflammatory eye disease remains controversial because of the potentially increased retention time of tears enriched with inflammatory cytokines that may aggravate eye inflammation. We describe the safety and efficacy of punctal occlusion in a retrospective analysis of 19 patients (16 men) with KCS due to chronic GvHD (cGvHD). Efficacy and safety were assessed by subjective and objective criteria (symptoms, corneal fluorescein staining, tear film break-up time (BUT), Schirmer I test, Jones test and visual acuity). Follow-up was from plug insertion until maximum one year after punctal occlusion. After punctal occlusion, patients reported a significant increase in subjective comfort (1.10 vs 0.59 on a scale ranging from no symptoms (0) to severe impairment (2), Po0.001). Pathological corneal fluorescein staining decreased significantly (Po0.001) and tear film BUT remained unchanged (5.98 vs 4.0 s, P ¼ 0.79). Measurement of tear secretion or retention time showed a non-significant trend for improvement in the Schirmer I (3.0 vs 3.40 mm, P ¼ 0.08) and Jones (1.36 vs 2.8 mm, P ¼ 0.08) tests. The logMAR visual acuity remained unchanged. Punctal occlusion achieved a significant improvement in subjective symptoms and objective findings in ocular GvHD without increasing ocular inflammation.

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“…A oclusão do ponto lacrimal ajuda a reter, na superfície ocular, tanto a lágrima natural quanto as lágrimas artificiais, bloqueando a sua drenagem (18) . Esta oclusão pode (19)(20) . Os plugs são utilizados com maior freqüência pelo fato de ser um procedimento ambulatorial e reversível.…”

Section: Discussionunclassified

Implante de plug lacrimal termosensível para tratamento da síndrome da disfunção lacrimal

Silvério¹,

Ferreira²,

Paulino³

et al. 2010

Rev. bras.oftalmol.

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RESUMOObjetivo: Avaliar os resultados da oclusão de ponto lacrimal reversível com o uso de plugs termosensíveis para o tratamento da síndrome da disfunção lacrimal. Métodos: Dezoito olhos de 9 pacientes com diagnóstico de olho seco foram selecionados e submetidos à oclusão reversível de ponto lacrimal com o uso de plugs termosensíveis, e acompanhados por 60 dias através de questionário OSDI e testes com fluoresceína, rosa bengala e Schirmer. Resultados: Em todos os pacientes estudados houve melhora nos sintomas de olho seco e melhora nos parâmetros oftalmológicos pesquisados. Em apenas 1 dos pacientes a melhora dos sintomas foi pequena, e não houve diminuição na dependência de colírio lubrificante. Nos outros 8 pacientes houve diminuição no uso de colírio. Durante o estudo não ocorreram complicações infecciosas ou de extrusão. Conclusão: Oclusão temporária do ponto lacrimal com SmartPlug tm parece ser uma opção efetiva para o tratamento da síndrome da disfunção lacrimal quando o uso de lubrificantes não é suficiente. Sua colocação é relativamente simples e segura, porém estudos mais longos são necessários.

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The Clinical Efficacy of Silicone Punctal Plug Therapy

Cited by 136 publications

References 16 publications

Neurotrophic Keratitis

Neurotrophic Keratitis

Punctal occlusion is safe and efficient for the treatment of keratoconjunctivitis sicca in patients with ocular GvHD

Implante de plug lacrimal termosensível para tratamento da síndrome da disfunção lacrimal

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