The clinical feasibility and effect of online cone beam computer tomography-guided intensity-modulated radiotherapy for nasopharyngeal cancer

Prospective Trial of High-Dose Reirradiation Using Daily Image Guidance With Intensity-Modulated Radiotherapy for Recurrent and Second Primary Head-and-Neck Cancer

“…The magnitudes of the shifts performed with IGRT are fairly consistent with those reported by others in the setting of head-and-neck cancer irradiation (17,18). Den et al (17) studied 28 patients and reported a mean interfraction shift of 1.4 mm, 1.7 mm, and 1.8 mm in the ML, SI, and AP dimensions, respectively.…”

“…Den et al (17) studied 28 patients and reported a mean interfraction shift of 1.4 mm, 1.7 mm, and 1.8 mm in the ML, SI, and AP dimensions, respectively. Wang et al (18) similarly reported systematic and random errors generally on the order of 1.1-1.3 mm for 22 patients treated for nasopharyngeal cancer. Similar to the present findings, these results from Thomas Jefferson University and Sichuan University, respectively, found that shifts exceeded a 3-mm threshold in 10-17% and 6-10% of cases.…”

Intensity-Modulated Radiotherapy for Prostate Cancer Implementing Molecular Imaging with 18F-Choline PET-CT to Define a Simultaneous Integrated Boost

“…The SIB concept has been rapidly adopted for the IMRT of head and neck cancer patients [39,40]. Dose escalation in the area of the primary macroscopic tumor is also applied in several other regions, probably most frequently for breast cancer -the clinical benefit on local control has been demonstrated [2,31].…”

Atlas-Based Semiautomatic Target Volume Definition (CTV) for Head-and-Neck Tumors

“…In consequence, precise knowledge of the patient position before each irradiation is of paramount importance. Cone-beam CT will probably be used in many departments in the future to control patient positioning and alignment (25). Head-and-neck cancer patients show considerable local setup variations (26,27).…”