The clinical investigation of 153 liver abscesses in the past 20 years

Shigefuku, Ryuta; Watanabe, Tsunamasa; Hattori, Nobuhiro; Ikeda, Hiroki; Matsunaga, Kotaro; Matsumoto, Nobuyuki; Ehira, Takuya; Suzuki, Tomohiko; Oumi, Ryosuke; Igarashi, Yosuke; Tsuji, K; Morita, Nozomi; Morita, Ryo; Michikawa, Yosuke; Nakahara, Kazunari; Suetani, Keigo; Nakano, Hirofumi; Hiraishi, Tetsuya; Noguchi, Yoshiko; Takahashi, Hideaki; Ishii, Toshimasa; Kunishima, Hiroyuki; Okuse, Chiaki; Suzuki, Michihiro; Itoh, Fumio

doi:10.2957/kanzo.59.466

Cited by 6 publications

(2 citation statements)

References 33 publications

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“…It is important to identify the pathogenic microorganism in order to make appropriate antibiotic choices. In patients with liver abscess, the detection rate of blood culture was 44%, whereas that of abscess culture was as high as 83% (7). Abscess culture should be performed early to direct proper treatment (2).…”

Section: Discussionmentioning

confidence: 99%

“…A. aphrophilus sometimes causes systemic diseases, particularly bone and joint infections, spondylodiscitis, and endocarditis ( 5 - 7 ), but rarely causes liver abscesses. A. aphrophilus is difficult to identify using culture methods; however, it is important to identify pathogenic microorganisms in order to provide adequate antimicrobial therapy for pyogenic liver abscess.…”

Section: Introductionmentioning

confidence: 99%

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The First Known Case of Liver Abscess Caused by <i>Aggregatibacter aphrophilus</i> in Japan

Okumura¹,

Soya²,

Hihara³

et al. 2020

Intern. Med.

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A 48-year-old man presented with a sustained fever. Abdominal computed tomography revealed multilocular liver abscesses. He underwent percutaneous needle aspiration, yielding straw-colored pus. Gram staining revealed Gram-negative coccobacilli. The organism grew only on chocolate II agar in a 7% carbon dioxide atmosphere. Identification of Aggregatibacter aphrophilus was confirmed using mass spectrometry and 16S rRNA gene sequencing. He was successfully treated with antibiotics. Liver abscess caused by A. aphrophilus is extremely rare. We herein report the first such case in Japan. Even fastidious organisms, such as A. aphrophilus, should be correctly identified using mass spectrometry or 16S rRNA gene sequencing for adequate treatment.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%