The clinical presentation of reflux oesophagitis, hiatal hernia, Barrett's oesophagus and reflux-like dyspepsia: a prospective clinical and endoscopic study

Long-Term Outcome Of Patients With Functional Dyspepsia Infected With A Cag-Positive Helicobacter Pylori Strain. A Descriptive Study

“…The scores in the general questionnaire are lower than reported in a previous study in patients with active disease [22]. It can be concluded that patients with functional dyspepsia and H.pylori gastritise infected with a more virulentH.pylori strain (this is CagA-positive), may develop more often complaints in the future necessitating a new endoscopic investigations and treatment.…”

“…After 2 years, a 35% reduction in consultations for dyspepsia occurred. An extension of this study showed an ongoing trent in reduction of consultations in the next 2 and 7 years [22]. In another study it was shown that only 36% of functional dyspeptics were without any complaint seven years after treatment with anti-Helicobacter treatment [23].…”

Newly developing hiatus hernia: A survey in patients undergoing upper gastrointestinal endoscopy

“…The presence of a hiatus hernia is not a prerequisite in developing reflux disease, but it does happen to be a major risk factor. It is well known that the majority of patients with active reflux esophagitis have a hiatus hernia as a concomitant abnormality 5,6 . The prevalence of hiatus hernia increases with age 7 .…”

“…The prevalence of hiatus hernia increases with age 7 . Patients with a hiatus hernia are older than patients who have gastroesophageal reflux complaints but no hernia 5 …”

Long-term use of acid-suppressive therapy after the endoscopic diagnosis of reflux esophagitis

“…Clinical presentation varies from typical symptoms without esophagitis to severe mucosal defects at endoscopy. The correlation between symptoms and the severity of esophagitis is poor 4 , 5 …”