The clinical value of combining shear wave elastography, VOCAL technique, and T2* MRI of early gestation placenta to predict pre‐eclampsia

Abstract

ObjectiveTo investigate the clinical value of combining shear wave elastography (SWE) with the Volumetric Organ Computer‐Aided AnaLysis (VOCAL) technique and T2* magnetic resonance imaging (MRI) to predict pre‐eclampsia (PE).MethodsFrom December 2022 to March 2023, we recruited 31 pregnant women diagnosed with PE at our hospital as the observation group and 85 normal pregnant women as the control group. Differences in placental elasticity, vascularization index (VI), flow index (FI), vascularization flow index (VFI), and T2* MRI perfusion fraction (f) were compared between the two groups. Received operating characteristic (ROC) curve analysis was performed to evaluate the diagnostic value of placental elasticity, VI, FI, VFI, f, and their combination for predicting PE.ResultsPlacental elasticity was higher in the observation group than in the control group, while VI, FI, VFI, and f were lower in the observation group (all p < 0.05). The area under the curve (AUC) for placental elasticity, VI, FI, VFI, f, and their combination for predicting PE were 0.85, 0.77, 0.78, 0.84, 0.65, and 0.94, respectively. The sensitivity was 71%, 55%, 94%, 65%, 55%, and 81%. The specificity was 92%, 91%, 60%, 92%, 79%, and 98%. The combined prediction model had a higher AUC than the individual predictors (p < 0.05).ConclusionSWE combined with VOCAL technique and T2* MRI has high value for predicting PE and can provide reference information for clinical diagnosis.

Predictive value of placental real-time shear wave elastography combined with 3-dimensional power Doppler index for preeclampsia

“…However, noninvasive and inexpensive character of ultrasound examination has enabled the use of ultrasound for very early detection (in the first and the second trimester) of pregnancy-specific diseases, such as gestational diabetes and PE. [8][9][10] Women with hypertensive disorders of pregnancy have increased shear wave elastography (SWE) of the placenta Informed consent was obtained from all individual participants included in the study.…”