The Co-occurrence of Personality Disorders and Substance Use Disorders

Stetsiv, Khrystyna; McNamara, Ian A.; Nance, Melissa; Carpenter, Ryan W.

doi:10.1007/s11920-023-01452-6

Curr Psychiatry Rep

2023

DOI: 10.1007/s11920-023-01452-6

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The Co-occurrence of Personality Disorders and Substance Use Disorders

Khrystyna Stetsiv,

Ian A. McNamara,

Melissa Nance

et al.

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2024

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Cited by 5 publications

References 90 publications

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Unraveling Relapse in Male Forensic Psychiatric Patients with Substance Use Disorders—The Impact of Social, Psychiatric, and Personality Factors Post Long-Term Remission

Fritz,

Montiel,

Al Dirany

et al. 2024

Int J Ment Health Addiction

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Substance use disorder, labelled a chronic relapse condition by the WHO, remains challenging to address with limited progress in effective relapse prevention measures. Scientific evaluation is hindered by cost, but an opportunity arises in the German forensic psychiatric setting governed by § 64 of the German criminal code. Here, patients undergo two-year multi-modal therapy followed by up to five years of supervised oversight post-release. This retrospective study analyzed legal and medical records, revealing key determinants of relapse, including emotional stress, social activities, personality disorder diagnosis, inpatient treatment relapse, age at first conviction, and loss of motivation. Surprisingly, social factors like family and work status, living situation at discharge, and dialectical behavioral therapy during admission showed no impact, nor did index crime type. Polysubstance use, except for cannabinoids and psychostimulants other than cocaine, increased relapse probability. Multiple inpatient pretreatments were insignificant predictors. A generalized linear model highlighted substance use during inpatient treatment, personality disorder, and previous convictions as most central predictors of post-discharge relapse, challenging conventional notions and informing effective substance use disorder management.

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Unraveling Relapse in Male Forensic Psychiatric Patients with Substance Use Disorders—The Impact of Social, Psychiatric, and Personality Factors Post Long-Term Remission

Fritz,

Montiel,

Al Dirany

et al. 2024

Int J Ment Health Addiction

View full text Add to dashboard Cite

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The unusual suspects: A systematic search for the molecular and cellular correlates of human aggression

Paiva,

Buades-Rotger,

Baskin-Sommers

et al. 2024

Aggression and Violent Behavior

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Burden and impact of substance abuse among epileptic patients attending epilepsy outpatient clinic

Abdou,

Karim,

Abozaid

et al. 2024

Egypt J Neurol Psychiatry Neurosurg

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Background To date, the burden and impact of substance use among epileptic patients were studied in a small number of studies and showed inconsistent findings, which may be attributed to the variation in age, test batteries, epilepsy subtypes, and substance use characteristics across research. The aim of the study was to determine the burden and impact of substance abuse among a sample of epileptic patients attending Alexandria University outpatient clinics. This study was conducted on 200 epileptic patients (100 male and 100 female patients). The diagnosis of epilepsy in those patients was confirmed by expert neurologists. Using the international league against epilepsy 2017 classification, they underwent a complete physical examination. EEG was done for all patients. Every patient was assessed using a semi-structured interview and a self-designed questionnaire to collect data concerning history of epilepsy, seizure type, EEG findings, as well as questions derived from the Addiction Severity Index (ASI). The Timeline between epilepsy and substance abuse, as well as the Effect of substance intake on epileptic seizures, were assessed. Results A total of 27 epileptic patients had a history of substance abuse; hence, the percentage of substance use among epileptic patients was 13.5%. Mean age in the male age group was (29.74 ± 11.52) years and (27.34 ± 9.35) years in females; mean seizure frequency per month was higher among males than females and this was statistically significant (P = 0.037*). More male (24%) than females (3%) had history of substance use and this was statistically significant (P < 0.001*). Regarding the Effect of substance intake on epileptic seizures, the male group (91.7%) had Seizure worsening, while in the female group, all three patients (100%) had seizures worsening with substance use. The mean Frequency of seizures was 4.48 ± 5.08 attacks per month for substance users and 2.49 ± 3.84 attacks per month for non-users; this was statistically significant. (t = 2.392) (P = 0.018*). Non-substance use patients had better compliance to treatment (79%) in comparison to 44.4%) of Substance use patients and this was statistically significant (P < 0.001*). Conclusion Drug abuse can have a negative impact on epilepsy in both sexes regarding seizure severity frequency, and even compliance with medication.

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The Co-occurrence of Personality Disorders and Substance Use Disorders

Cited by 5 publications

References 90 publications

Unraveling Relapse in Male Forensic Psychiatric Patients with Substance Use Disorders—The Impact of Social, Psychiatric, and Personality Factors Post Long-Term Remission

Unraveling Relapse in Male Forensic Psychiatric Patients with Substance Use Disorders—The Impact of Social, Psychiatric, and Personality Factors Post Long-Term Remission

The unusual suspects: A systematic search for the molecular and cellular correlates of human aggression

Burden and impact of substance abuse among epileptic patients attending epilepsy outpatient clinic

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