The coexistence of systemic lupus erythematosus with other autoimmune diseases: The kaleidoscope of autoimmunity

Lorber, Margalit; Gershwin, M. Eric; Shoenfeld, Yehuda

doi:10.1016/s0049-0172(05)80004-6

Cited by 64 publications

(52 citation statements)

References 65 publications

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“…Hudson et al [16] studied on 719 patients with systemic sclerosis and reported that family history of an AID was a significant predictor of PAI in those patients. Similarly, familial autoimmunity was defined as a risk factor for PAI in SLE; and type 1 DM patients [17]. …”

Section: Discussionmentioning

confidence: 99%

Risk Factors for Polyautoimmunity among Patients with Celiac Disease: A Cross-Sectional Survey

et al. 2015

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Aim: To define the prevalence of polyautoimmunity (PAI) among celiac disease (CD) patients and to compare clinical and laboratory features of CD patients with or without PAI in order to determine the risk factors for PAI in CD. Material and Method: Patients diagnosed with CD in our clinic between 2007 and 2014 with at least 1 year of follow-up were retrospectively evaluated. Totally 145 patients were included in the study. Information on patient demographics and laboratory data were obtained from patient records. The study participants were divided into 2 groups. Group 1 was the CD-alone group consisting of patients without any other autoimmune diseases (AIDs), while group 2 was the PAI group consisting of patients with accompanying one or more AIDs. Results: The mean age of 145 CD patients (106 female and 39 male) included in the study was 37.2 ± 12.3 years. Of the 145 patients included, 48 (33.1%) were in the PAI group. When two groups were compared with each other in terms of the demographic features and laboratory data, the following were identified as risk factors for PAI: female gender, family history for AIDs, antigliadin IgG positivity, vitamin D deficiency, antinuclear antibody positivity ≥1/80 titer and having any musculoskeletal disease. Conclusion: To the best of our knowledge, this is one of the largest studies in the literature on CD patients for the PAI prevalence and related risk factors. Identification of the risk factors in early stages is important to explore PAI among CD patients. Larger, prospective studies are warranted about the risk factors and autoimmune characteristics of CD.

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Section: Discussionmentioning

confidence: 99%

Risk Factors for Polyautoimmunity among Patients with Celiac Disease: A Cross-Sectional Survey

et al. 2015

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“…Any CTD can be a partner in an overlap disorder. 4 Mixed connective tissue disease (MCTD) is the prototype of an overlap syndrome. Since its original description by Sharp and collaborators in 1972, as an apparently unique syndrome combining clinical elements of SSc, SLE and PM, associated with antibodies to RNAse sensitive extractable nuclear antigen, many clinical, serologic, and genetic studies have analysed the different aspects of this entity.…”

Section: Discussionmentioning

confidence: 99%

Mixed connective tissue disease presenting with isolated pulmonary hypertension, and limited cutaneous sclerosis

et al. 2016

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“…3 The existence of patients with signs, symptoms and certain laboratory test results suggestive of a systemic autoimmune disease but fulfilling more than one classification criteria for welldefined CTDs is a more and more common experience in clinical practice. As opposed to some early stages of CTDs that might be undefined, unclassifiable or perhaps incomplete, with clinical elements and laboratory results suggestive of a systemic disease but not fulfilling criteria for well-defined CTDs, overlap syndromes define patients exhibiting enough features to meet the diagnosis of several CTDs at the same time.…”

Section: Discussionmentioning

confidence: 99%

A rare case of mixed connective tissue disease presenting with central nervous system glioma, vasculitis and polymyositis

et al. 2015

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The coexistence of systemic lupus erythematosus with other autoimmune diseases: The kaleidoscope of autoimmunity

Cited by 64 publications

References 65 publications

Risk Factors for Polyautoimmunity among Patients with Celiac Disease: A Cross-Sectional Survey

Risk Factors for Polyautoimmunity among Patients with Celiac Disease: A Cross-Sectional Survey

Mixed connective tissue disease presenting with isolated pulmonary hypertension, and limited cutaneous sclerosis

A rare case of mixed connective tissue disease presenting with central nervous system glioma, vasculitis and polymyositis

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