The Cognitive Function at Work Questionnaire in memory clinic setting: a validation study

Heikkinen, Anna-Leena; Paajanen, Teemu I.; Hublin, Christer; Valtonen, Teppo; Krüger, Johanna; Tikkanen, Veera; Saari, Toni; Koivisto, Anne M.; Hänninen, Tuomo; Remes, Anne M.

doi:10.1080/13803395.2023.2239508

Journal of Clinical and Experimental Neuropsychology

2023

DOI: 10.1080/13803395.2023.2239508

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The Cognitive Function at Work Questionnaire in memory clinic setting: a validation study

Anna-Leena Heikkinen,

Teemu I. Paajanen,

Christer Hublin

et al.

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2024

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A Novel Computerized Flexible Attention Test in Detecting Executive Dysfunction of Patients with Early-Onset Cognitive Impairment and Dementia

Tikkanen,

Krüger,

Heikkinen

et al. 2024

Archives of Clinical Neuropsychology

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Objective The number of computer-based cognitive tests has increased in recent years, but there is a need for tests focusing on the assessment of executive function (EF), as it can be crucial for the identification of early-onset neurodegenerative disorders. This study aims to examine the ability of the Flexible Attention Test (FAT), a new computer-based test battery for detecting executive dysfunction of early-onset cognitive impairment and dementia patients. Method We analyzed the FAT subtask results in memory clinic patients with cognitive symptom onset at ≤65 years. The patients were divided into four groups: early onset dementia (EOD, n = 48), mild cognitive impairment due to neurological causes (MCI-n, n = 34), MCI due to other causes (MCI-o, n = 99), and subjective cognitive decline (SCD, n = 14). The test accuracy to distinguish EOD patients from other groups was examined, as well as correlations with pen-and-paper EF tests. We also reported the 12-months follow-up results. Results The EOD and MCI-n patients performed significantly poorer (p ≤ .002) than those in the MCI-o and SCD groups in most of the FAT subtasks. The accuracies of the FAT subtasks to detect EOD from other causes were mainly moderate (0.34 ≤ area under the curve < 0.74). The FAT subtasks correlated logically with corresponding pen-and-paper EF tests (.15 ≤ r ≤ .75). No systematic learning effects were detected in the FAT performance at follow-up. Conclusions The FAT appears to be a promising method for the precise evaluation of EF and applicable distinguishing early-onset neurodegenerative disorders from patients with other causes of cognitive problems.

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A Novel Computerized Flexible Attention Test in Detecting Executive Dysfunction of Patients with Early-Onset Cognitive Impairment and Dementia

Tikkanen,

Krüger,

Heikkinen

et al. 2024

Archives of Clinical Neuropsychology

View full text Add to dashboard Cite

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The Cognitive Function at Work Questionnaire in memory clinic setting: a validation study

Cited by 1 publication

References 57 publications

A Novel Computerized Flexible Attention Test in Detecting Executive Dysfunction of Patients with Early-Onset Cognitive Impairment and Dementia

A Novel Computerized Flexible Attention Test in Detecting Executive Dysfunction of Patients with Early-Onset Cognitive Impairment and Dementia

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