The cohort of antral follicles measuring 2–6 mm reflects the quantitative status of ovarian reserve as assessed by serum levels of anti-Müllerian hormone and response to controlled ovarian stimulation

Jayaprakasan, Kannamannadiar; Deb, Shilpa; Batcha, M.; Hopkisson, James; Johnson, I. R.; Campbell, Bruce; Raine‐Fenning, Nick

doi:10.1016/j.fertnstert.2009.10.022

Cited by 88 publications

(67 citation statements)

References 39 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…11,12 Despite the fact, that at present there is no agreement on identification of the antral follicles by size, the majority of researchers imply the amount of 2-10 mm follicles counted in early follicular phase. 13,14 It has been reported that human antral follicles measuring <6 mm express the great amount of AMH, and levels decline with antral follicles increase in size. 15 In the study by Goksedef et al, the best correlation was found between AMH levels and 5-6 mm antral follicles.…”

Section: Discussionmentioning

confidence: 99%

Study of ovarian reserve parameters in infertile women of different age groups

Valvekar¹,

Lakshmi

Kumar

2016

Int J Reprod Contracept Obstet Gynecol

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

Study of ovarian reserve parameters in infertile women of different age groups

Valvekar¹,

Lakshmi

Kumar

2016

Int J Reprod Contracept Obstet Gynecol

View full text Add to dashboard Cite

“…There is no consensus on identification of the antral follicles (2), however several evidence based studies suggested to select the follicles as antral follicles based on a diameter measurement as 2 to 10 mm. (3)(4)(5)(6)(7)(8)(9)(10). It has been reported that human antral follicles measuring <6 mm express the greatest amount of AMH, and that levels decline with antral follicles increase in size (23).…”

Section: Discussionmentioning

confidence: 99%

“…The antral follicle count (AFC) have been widely used as the ovarian reserve test, due to convenience of the ultrasonographic tools usage. Follicle counts can be performed easily with the help of the high quality resolution of the sonographic systems (2)(3)(4)(5)(6)(7)(8)(9)(10). Although there are well-known difficulties to obtain correct AFC such as high inter-observer differences and anatomical variations (3), it has been suggested that the ability of AFC to predict poor response might be significantly better than basal FSH.…”

Section: Introductionmentioning

confidence: 99%

“…In the ovary, AMH inhibits initial primordial follicles recruitment and decreases the sensitivity of preantral and small antral follicles to FSH and hence suggesting its role in intrafollicular and interfollicular coordination of follicle development (17,18). Recently it has been shown that the higher AMH levels were associated with the greater numbers of retrieved oocytes and improved embryo morphology in the IVF cycles (10,15,19,20). There has been a controversary between the corelation of the AFC and the other ovarian reserve tests such as age, AMH, basal FSH, E 2 and inhibin-B.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

The correlation of the antral follicle count and Serum anti-mullerian hormone

Goksedef

Idiş

Görgen

et al. 2010

J Turkish German Gynecol Assoc

View full text Add to dashboard Cite

Objective:To compare the value of the basal serum anti-Müllerian hormone (AMH) level with most of the established ovarian reserve tests. Material and Methods:A total of 141 infertile women was studied prospectively. On cycle day 3, serum levels of AMH, inhibin B, estradiol (E), FSH and LH levels were measured, and the number of early antral follicles (2-6 mm in diameter) estimated at ultrasound scanning to compare the strengths of hormonal-follicular correlations. Results:The mean age of the participants was 29.18±5.54. The mean AMH and total AFC on day 3 were 2.23±1.90 ng/ml and 8.35±2.83, respectively. Serum AMH levels were more tightly correlated (p<0.001) with number of the early antral follicle count (r=0.467, p<0.0001) than age and serum levels of FSH (r=-0.400, p<0.001; r=-0.299, p<0.001 respectively). No correlation was detected between serum levels of inhibin B, E 2 , and LH (r=0.154, p=0.06; p=0.31; r=-0.085 and r=0.067, p=0.42) and AFC. Conclusion:Serum AMH levels showed a strong correlation with AFC, and also this correlation is stronger than the other ovarian reserve parameters. (J Turkish-German Gynecol Assoc 2010; 11: 212-5) Key words: Anti-mullerian hormone; ovarian reserve; antral follicle count Received: 9 October, 2010 Accepted: 22 November, 2010 Amaç: Bu çalışmada basal serum bazal anti-Müllerian hormone (AMH) seviyesinin diğer sık kullanılan over rezerv testleri ile karşılaş-tırılması amaçlanmıştır. Gereç ve Yöntemler:

show abstract

“…There are some predictors for the number of retrieved immature oocytes, such as the number of 2 to 6-mm antral follicles, ovarian volume and peak ovarian stromal blood flow velocity measured by doppler ultrasound during the follicular phase. Also, there have been direct relations between the number of immature oocytes and pregnancy rates following IVM of human oocytes [4,13,31]. However, there are no strict data about the probable impact of these immature oocytes on maturity and outcome of their mature cohort oocytes in ART program.…”

Section: Introductionmentioning

confidence: 99%

The effect of immature oocytes quantity on the rates of oocytes maturity and morphology, fertilization, and embryo development in ICSI cycles

Halvaei

Khalili

Razi

et al. 2012

J Assist Reprod Genet

View full text Add to dashboard Cite

Purpose The goal was to evaluate the role of the number of retrieved immature oocytes on mature oocyte counts and morphology, and also the rates of fertilization and embryo development in ICSI cycles. Methods 101 ICSI cycles were included in this prospective evaluation. Patients were divided into 2 groups of A (≤ 2 immature oocytes) and B (> 2 immature oocytes). In subanalysis, the impacts of the number of GV and MI oocytes were assessed on the rates of fertilization and embryo development. Also, correlations between the numbers of immature and mature oocytes, as well as maternal age between two groups were analyzed. Assessments of oocyte morphology, fertilization, embryo quality and development were done accordingly. Results There was no correlation between the immature oocytes quantity with the number of mature ones. There were insignificant differences for embryo development between two groups, but fertilization rate was higher in group A (P00.03). In sub-analysis, insignificant differences were observed between two groups of ≤ and >2 GV and MI oocytes for rates of fertilization and embryo development. Also, the rates of clinical pregnancy and delivery were insignificant between groups. The rate of morphologically abnormal oocytes had no significant difference between two groups, except for wide perivitelline space (PVS) which was higher in group A (P00.03). There was no significant difference for maternal age between two groups. Conclusions In cases with few retrieved immature oocytes, rates of fertilization and incidence of wide PVS may increase, although immature oocytes may not have any negative impacts on early embryo development, or the rates on number of mature oocytes.

show abstract

The cohort of antral follicles measuring 2–6 mm reflects the quantitative status of ovarian reserve as assessed by serum levels of anti-Müllerian hormone and response to controlled ovarian stimulation

Cited by 88 publications

References 39 publications

Study of ovarian reserve parameters in infertile women of different age groups

Study of ovarian reserve parameters in infertile women of different age groups

The correlation of the antral follicle count and Serum anti-mullerian hormone

The effect of immature oocytes quantity on the rates of oocytes maturity and morphology, fertilization, and embryo development in ICSI cycles

Contact Info

Product

Resources

About