2021
DOI: 10.1101/2021.02.01.429218
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The Collagens DPY-17 and SQT-3 Direct Anterior-Posterior Migration of the Q Neuroblasts inC. elegans

Abstract: Cell adhesion molecules and their extracellular ligands control morphogenetic events such as directed cell migration. The migration of neuroblasts and neural crest cells establishes the structure of the central and peripheral nervous systems. In C. elegans, the bilateral Q neuroblasts and their descendants undergo long-range migrations with left/right asymmetry. QR and descendants on the right migrate anteriorly, and QL and descendants on the left migrate posteriorly, despite identical patterns of cell divisio… Show more

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Cited by 2 publications
(1 citation statement)
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“…This characteristic stopping point suggests that lev-11 affects a developmental guidepost rather than generally affecting the ability of AQR to migrate, which results in stoppages of AQR along anterior body in positions 2, 3, and 4 ( e.g. epi-1/laminin mutants) (Lang and Lundquist 2021). Two-hybrid studies suggest that LEV-11 physically interacts with MIG-14/Wntless (Koorman et al .…”
Section: Discussionmentioning
confidence: 99%
“…This characteristic stopping point suggests that lev-11 affects a developmental guidepost rather than generally affecting the ability of AQR to migrate, which results in stoppages of AQR along anterior body in positions 2, 3, and 4 ( e.g. epi-1/laminin mutants) (Lang and Lundquist 2021). Two-hybrid studies suggest that LEV-11 physically interacts with MIG-14/Wntless (Koorman et al .…”
Section: Discussionmentioning
confidence: 99%