Objective To investigate which of two commonly used treatment protocols for exercise-associated postural hypotension (EAPH) resulted in earlier discharge from the medical facility. Methods This randomised clinical fi eld trial was undertaken at two Ironman Triathlon competitions and one ultra-distance footrace. All collapsed athletes admitted to the medical facilities were considered for the trial. Following clinical assessment and special investigations to confi rm the diagnosis of EAPH, 28 athletes were randomly assigned to an oral fl uid and Trendelenburg position (OT=14) or an intravenous fl uid (IV=14) treatment group. Following admission fl uid intake was recorded, and all athletes were assessed clinically (blood pressure, heart rate, level of consciousness) every 15 min until discharge criteria were met. The main measure of outcome was the time to discharge (min). Results On admission, subjects in the OT and IV groups were similar with respect to age, systolic blood pressure, heart rate and serum sodium concentration. There were no signifi cant differences in heart rate, systolic and diastolic blood pressure between groups and over time until discharge. The fl uid intake during the treatment period was signifi cantly greater in the IV group (IV 1045±185 ml, OT 204±149 ml; p<0.001). The average time to discharge for the OT group (58±23 min) was similar to that of the IV group (52.5±18 min; p=0.47). Conclusion Endurance athletes with EAPH can be treated effectively using the Trendelenburg position and oral fl uids and the administration of intravenous fl uids does not reduce the time to discharge. The fi ndings of this study support the hypothesis that EAPH is a result of venous pooling due to peripheral vasodilatation, rather than dehydration.Due to the strenuous nature of ultra-endurance events, participants in these events are at risk of developing various medical conditions. 1-7 One of the most common clinical presentations during and following an endurance event is that of the 'collapsed' athlete. Various medical conditions may lead to collapse in athletes, including cardiovascular, metabolic, neurological, musculoskeletal and respiratory causes. [1][2][3][4][5][6][7] The most common cause for collapse is a condition referred to as exercise-associated postural hypotension (EAPH). 3 8-10 The exact pathophysiology of EAPH is still widely debated in the literature, and currently two hypotheses have been proposed. The fi rst hypothesis is that a combination of dehydration and hyperthermia causes circulatory failure, resulting in the collapse of the athlete. 3 5 11-14The second hypothesis is that pooling of blood occurs in the dilated venous system resulting in postural hypotension and thus collapse if generalised arterial vasoconstriction fails to occur immediately exercise terminates. 2 9 10 15-17As a result of this ongoing debate, there is no clarity on how best to treat athletes with EAPH. Instead two protocols are used to manage athletes with EAPH in race medical facilities. These are (1) intra...