The Combined Use of Nd:YAG Laser and Enamel Matrix Proteins in the Treatment of Periodontal Infrabony Defects

Abstract

Within the limits of the present study, it may be concluded that both therapies led to improvements of the clinical parameters, and Nd:YAG laser root conditioning as used in this study compared to EDTA root conditioning did not improve the outcome of EMP use.

Effectiveness of Laser Application for Periodontal Surgical Therapy: Systematic Review and Meta‐Analysis

“…Other studies 26 , 37 , 39 are in agreement with the present findings. In a comparative evaluation 37 of the efficiency of the diode laser as an adjunct to mechanical debridement versus conventional mechanical debridement in periodontal open flap surgery, no difference was found between laser‐treated and non–laser‐treated groups with regard to clinical parameters.…”

“…Contrary to previous findings 38 , 40 , 42 and in agreement with ours, Dilsiz et al 39 compared the clinical outcomes of enamel matrix proteins (EMP) alone and combined with Nd:YAG laser in the treatment of infrabony defects. They reported that the use of Nd:YAG laser did not have superiority over EDTA as a root conditioning agent 39 .…”

“…Contrary to previous findings 38 , 40 , 42 and in agreement with ours, Dilsiz et al 39 compared the clinical outcomes of enamel matrix proteins (EMP) alone and combined with Nd:YAG laser in the treatment of infrabony defects. They reported that the use of Nd:YAG laser did not have superiority over EDTA as a root conditioning agent 39 . Along these lines, it is important to mention that consensus is lacking that EMP as a biologic agent enhances clinical outcomes compared to GTR procedures using barrier membranes 61–64 .…”

Enamel Matrix Derivative in Propylene Glycol Alginate for Treatment of Infrabony Defects With or Without Systemic Doxycycline: 12‐ and 24‐Month Results

“…This clinical trial revealed similar CAL‐V gain in infrabony defects with an INFRA of 4.8 mm (DOXY) and 5.2 mm (PLAC) 12 months after therapy using EMD compared with results reported by others 12 months after EMD in similar or more favorable defects: In moderately deep (5.6 mm) 1‐ and 2‐wall defects, CAL‐V gains of 1.9 mm were reported 27 and in deep (8.5 mm) non‐contained infrabony defects, CAL‐V gains of 2.4 mm were reported 32 . In deep (6.8 mm) 2‐ and 3‐wall defects, CAL‐V gains of 3 mm was observed 33 . Furthermore, 12 months after treatment, mean CAL‐V gain of 3.4 mm 34 and 4.7 mm was achieved in defects with 6.1 mm INFRA 35 .…”

Commentary: Is There Clinical Benefit From Using a Diode or Neodymium:Yttrium‐Aluminum‐Garnet Laser in the Treatment of Periodontitis?

“…Here again, none of the average differences, regardless of clinical parameter, can be considered clinically significant. The reductions in subgingival microbial loads are not significant primarily because six 37,38,42‐44,46 of the eight studies did not measure this parameter, and the remaining two studies found no significant difference between treatment groups.…”