This article touches upon the issue of the process of commodification of knowledge in the context of higher education system in Russia. The relevance of the research is first determined by the processes of Russian universities transformation into world-class universities in order to improve their positions in global university rankings, and, secondly, by the need for modification of the translation of scientific paradigm foundations and new knowledge acquisition through the means of commodification. Among various educational practices in the era of globalization, developing countries including Russia are implementing diverse representations of transnational collaboration in the field of education. For this reason, the process of commodification of knowledge may be also considered as one of the direction of the Russian educational system towards integration into global educational environment. The purpose of this research is to define the peculiarities of the concept of commodification of knowledge in the system of higher education and to analyze the main strategies of Russian universities reformation.