The Common Cold -- My Favourite Infection: The Eighteenth Marjory Stephenson Memorial Lecture

Tyrrell, D. A. J.

doi:10.1099/0022-1317-68-8-2053

Journal of General Virology

1987

DOI: 10.1099/0022-1317-68-8-2053

|View full text |Cite

The Common Cold -- My Favourite Infection: The Eighteenth Marjory Stephenson Memorial Lecture

D. A. J. Tyrrell¹

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

1990

2015

Publication Types

Select...

Article5

Relationship

Self Cite0

Independent5

Authors

Journals

Cited by 5 publications

References 24 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Prevention of Common Colds by Hydrotherapy: A Controlled Long-term Prospective Study

Ernst¹,

Wirz²,

Pecho³

1990

Physiotherapy

View full text Add to dashboard Cite

In a search for an effective prophylaxis against common colds, 25 volunteers were treated regularly with a standardised hydrotherapy programme for half a year, while 25 matched untreated persons served as controls. The frequency, duration and strength of colds were recorded. Resultsshow that there is a significant reduction in frequency of colds in the treated group. Similarly, this group seemed also to be affected less severely. The duration of common colds was shorter in the treated group which, however, failed to reach the level of significance. The prophylactic effects took about three months to become apparent. The underlying mechanism, by which the effect is mediated, is speculative at present. It is suggested that regular hydrotherapy represents an effective prophylaxis against common colds.

show abstract

Prevention of Common Colds by Hydrotherapy: A Controlled Long-term Prospective Study

Ernst¹,

Wirz²,

Pecho³

1990

Physiotherapy

View full text Add to dashboard Cite

show abstract

Rhinites aiguës

Gilain¹,

Guichard²

2006

EMC - Oto-rhino-laryngologie

View full text Add to dashboard Cite

Design, recruitment, and microbiological considerations in human challenge studies

Darton

Blohmke

Moorthy³

et al. 2015

The Lancet Infectious Diseases

120

113

View full text Add to dashboard Cite

Since the 18th century a wealth of knowledge regarding infectious disease pathogenesis, prevention, and treatment has been accumulated from findings of infection challenges in human beings. Partly because of improvements to ethical and regulatory guidance, human challenge studies-involving the deliberate exposure of participants to infectious substances-have had a resurgence in popularity in the past few years, in particular for the assessment of vaccines. To provide an overview of the potential use of challenge models, we present historical reports and contemporary views from experts in this type of research. A range of challenge models and practical approaches to generate important data exist and are used to expedite vaccine and therapeutic development and to support public health modelling and interventions. Although human challenge studies provide a unique opportunity to address complex research questions, participant and investigator safety is paramount. To increase the collaborative effort and future success of this area of research, we recommend the development of consensus frameworks and sharing of best practices between investigators. Furthermore, standardisation of challenge procedures and regulatory guidance will help with the feasibility for using challenge models in clinical testing of new disease intervention strategies.

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

The Common Cold -- My Favourite Infection: The Eighteenth Marjory Stephenson Memorial Lecture

Cited by 5 publications

References 24 publications

Prevention of Common Colds by Hydrotherapy: A Controlled Long-term Prospective Study

Prevention of Common Colds by Hydrotherapy: A Controlled Long-term Prospective Study

Rhinites aiguës

Design, recruitment, and microbiological considerations in human challenge studies

Contact Info

Product

Resources

About