The comorbidity of epilepsy and depression: diagnosis and treatment

Tao, Kaiyan; Wang, Xuefeng

doi:10.1080/14737175.2016.1204233

Cited by 24 publications

(21 citation statements)

References 110 publications

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“…Depressive symptoms were a moderate predictor of QoL [23,28]. Depression is known to be prevalent with those who have epilepsy [42][43][44][45]. Potential older adult related life changes, such as increased isolation, could worsen depressive symptoms.…”

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confidence: 99%

The quality of life of older adults with epilepsy: A systematic review

Baranowski

2018

Seizure

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The aim of this systematic review is to identify and synthesise the current literature on the quality of life (QoL) of older adults with epilepsy. Studies were included if they (1) assessed the QoL of older adults (2) had a minimum of one population group of people with epilepsy aged 60 and older and (3) used a standardised QoL measure. Databases searched were PubMed, Scopus, Cochrane Library and PubPsych. A total of 201 abstracts were screened, of which 10 articles met the criteria. A 17-item standardised checklist was used to analyse the methodological quality of the studies. This checklist was derived from other systematic reviews which analysed the QoL of those with other health conditions and modified to suit the purpose of this review. The findings were synthesised to compare the overall QoL of older adults in comparison to younger age groups and to identify which QoL factors were the most and least negatively impacted by the presence of epilepsy and old age. Predictors of QoL were identified from findings that used a regression analysis and were rated regarding their strength of evidence. No clear differences for overall QoL were found between older and younger people with epilepsy. Participants reported energy/fatigue to be the most negatively impacted factor. Seizure frequency was a strong predictor of QoL, and comorbidity and depression were moderate predictors. The modest number of studies available for synthesis is a reflection of the gap in current literature on this topic. Future research needs to include more variables within their regression analysis to identify more predictors of QoL, and needs to compare QoL changes over the trajectory of older age.

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confidence: 99%

The quality of life of older adults with epilepsy: A systematic review

Baranowski

2018

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“…Однією з найпоширеніших форм психопатологічної коморбідності при епілепсії визнають депресивні розлади, що є другими за частотою після коливань афекту [3]. Патоґенез депресивних розладів при епілепсії є поліфакторним та становить поєднання нейробіологічних, ятрогенних та психосоціальних факторів [3][4][5] [7][8][9].…”

Section: I Kharytonovunclassified

Personality of a patient in forming depressions in epilepsy

Kharytonov¹

2019

UVP

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In order to determine the psychological characteristics of the personality of patients with epilepsy and comorbidity depressions, were analised of characterological features, personality characteristics defining socio-psychological adaptation, forms of manifestation of aggressiveness in patients with organic, psychogenic and endogenous depressions in the interictal period of epilepsy. It has been established that patients with epilepsy and depression are characterized by the anadaptive nature of personal organization: persistent pessimism, decreased contact tendencies, rigidity of affective reactions, propensity to develop and accumulate hostile reactions with insuffi cient active realization of aggressive tendencies. The results of the study should be taken into account as targets in psychotherapeutic and psychoprophylactic work with patients with epilepsy. Key words: epilepsy, organic depressions, psychogenic depressions, endogenous depressions, interictal period, characterological features, sociopsychological adaptation, manifestations of aggression

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“…Симптоми депресії при епілепсії класифікують стосовно основ но го прояву захворювання -епілептичного нападу. Психопато логічна симптоматика може проявлятися в переднападному (преіктальному) періоді, в пост нападному (постіктальному) періоді, але найбільш часто вона безпосередньо не пов'язана з нападом (інтеріктальна симптоматика) [5]. Систематизація інтеріктальних депресій сильно ускладнена через різноманіття механізмів, що їх спричиняють.…”

Section: I Kharytonov Features Of the Psychopathological Conditiounclassified

Features of the psychopathological condition of patients with epilepsy and depression in an interictal period

Kharytonov¹

2019

UVP

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The paper presents the results of a comprehensive study of the characteristics of the psychopathological state of patients with epilepsy and depressions of various genesis (organic, psychogenic and endogenous) in the interi ctal period. Were investigated the severity and structure of psychopathological manifestations, as well as separately the level and structure of anxiety in patients with epilepsy depending on the form of depression in a comparative aspect with patients with epilepsy without signs of depression. According to the selected forms of depression, are analyzed the severity and structural features of depressive symptoms. Was established that patients with depressions are characterized by more pronounced and diverse psychopathological manifestations, in the structure of which, apart from depressive manifestations, anxious and psychosomatic symptoms are formed (with organic and psychogenic depressions); as well as asthenic manifestations, a decrease in the level of interpersonal interaction and obsessive-compulsive symptoms (with endogenous depressions). Is determined the highest level of psychopathological distress in patients with epilepsy with endogenous depressions. Key words: epilepsy, organic depression, psychogenic depression, endogenous depression, interictal period, psychopathological condition, anxiety, depressive manifestations.

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The comorbidity of epilepsy and depression: diagnosis and treatment

Cited by 24 publications

References 110 publications

The quality of life of older adults with epilepsy: A systematic review

The quality of life of older adults with epilepsy: A systematic review

Personality of a patient in forming depressions in epilepsy

Features of the psychopathological condition of patients with epilepsy and depression in an interictal period

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