The comparative landscape of duplications in Heliconius melpomene and Heliconius cydno

Pinharanda, Ana; Martin, Simon H.; Barker, SL; Jw, Davey; Jiggins, Chris D.

doi:10.1038/hdy.2016.107

Cited by 17 publications

(19 citation statements)

References 72 publications

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“…S87), and a strongly negative relationship between chromosome size and average recombination rate (Fig. S88), though this correlation is weaker than in H. melpomene (8,87), though the sample size for H. erato is much lower than that for H. melpomene.…”

Section: Section 8: Topology Distributionmentioning

confidence: 86%

Genomic architecture and introgression shape a butterfly radiation

Edelman

Frandsen

Miyagi

et al. 2019

Science

445

427

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We used 20 de novo genome assemblies to probe the speciation history and architecture of gene flow in rapidly radiating Heliconius butterflies. Our tests to distinguish incomplete lineage sorting from introgression indicate that gene flow has obscured several ancient phylogenetic relationships in this group over large swathes of the genome. Introgressed loci are underrepresented in low-recombination and gene-rich regions, consistent with the purging of foreign alleles more tightly linked to incompatibility loci. Here, we identify a hitherto unknown inversion that traps a color pattern switch locus. We infer that this inversion was transferred between lineages by introgression and is convergent with a similar rearrangement in another part of the genus. These multiple de novo genome sequences enable improved understanding of the importance of introgression and selective processes in adaptive radiation.

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Section: Section 8: Topology Distributionmentioning

confidence: 86%

Genomic architecture and introgression shape a butterfly radiation

Edelman

Frandsen

Miyagi

et al. 2019

Science

445

427

View full text Add to dashboard Cite

show abstract

“…To identify putative functions for each potential candidate, protein sequences from Lepbase were searched against the nr (non-redundant) protein database using BLASTp (Altschul et al 1990). For each candidate with a promising functional annotation, exons were pulled out of the H. cydno genome (Pessoa Pinharanda 2017) and aligned to the H. melpomene genes using BLASTn with each H. melpomene exon to search for SNPs between the two species. Selection was tested at the sequence level using codeml (Yang 2007) in pairwise mode with the F3X4 codon frequency model.…”

Section: Methodsmentioning

confidence: 99%

A major locus controls a biologically active pheromone component inHeliconius melpomene

Byers

Darragh

Musgrove

et al. 2019

Preprint

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Understanding the production, response, and genetics of signals used in mate choice can inform our understanding of the evolution of both intraspecific mate choice and reproductive isolation. Sex pheromones are important for courtship and mate choice in many insects, but we know relatively little of their role in butterflies. The butterfly Heliconius melpomene uses a complex blend of wing androconial compounds during courtship. Electroantennography in H. melpomene and its close relative Heliconius cydno showed that responses to androconial extracts were not species specific. Females of both species responded equally strongly to extracts of both species, suggesting conservation of peripheral nervous system elements across the two species. Individual blend components provoked little to no response, with the exception of octadecanal, a major component of the H. melpomene blend. Supplementing octadecanal on the wings of octadecanal-rich H. melpomene males led to an increase in the time until mating, demonstrating the bioactivity of octadecanal in Heliconius. Using quantitative trait locus (QTL) mapping, we identified a single locus on chromosome 20 responsible for 41% of the parental species' difference in octadecanal production. This QTL does not overlap with any of the major wing color or mate choice loci, nor does it overlap with known regions of elevated or reduced F ST . A set of 16 candidate fatty acid biosynthesis genes lies underneath the QTL. Pheromones in Heliconius carry information relevant for mate choice and are under simple genetic control, suggesting they could be important during speciation. K E Y W O R D S : Behavior, electroantennography, Heliconius, pheromones, quantitative trait locus mapping.

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“…2013), and many gene duplications have been identified between the two species (Pinharanda et al. 2017). …”

Section: Introductionmentioning

confidence: 99%

No evidence for maintenance of a sympatricHeliconiusspecies barrier by chromosomal inversions

et al. 2017

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Mechanisms that suppress recombination are known to help maintain species barriers by preventing the breakup of coadapted gene combinations. The sympatric butterfly species Heliconius melpomene and Heliconius cydno are separated by many strong barriers, but the species still hybridize infrequently in the wild, and around 40% of the genome is influenced by introgression. We tested the hypothesis that genetic barriers between the species are maintained by inversions or other mechanisms that reduce between‐species recombination rate. We constructed fine‐scale recombination maps for Panamanian populations of both species and their hybrids to directly measure recombination rate within and between species, and generated long sequence reads to detect inversions. We find no evidence for a systematic reduction in recombination rates in F1 hybrids, and also no evidence for inversions longer than 50 kb that might be involved in generating or maintaining species barriers. This suggests that mechanisms leading to global or local reduction in recombination do not play a significant role in the maintenance of species barriers between H. melpomene and H. cydno.

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The comparative landscape of duplications in Heliconius melpomene and Heliconius cydno

Cited by 17 publications

References 72 publications

Genomic architecture and introgression shape a butterfly radiation

Genomic architecture and introgression shape a butterfly radiation

A major locus controls a biologically active pheromone component inHeliconius melpomene

No evidence for maintenance of a sympatricHeliconiusspecies barrier by chromosomal inversions

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