The Comparison of Bone-Like Apatite Formation on Two Kinds of Bio-Active Material Surface Under the Low-Intensive Pulsed Ultrasound Waving (LIPUS) for Osseointegration

Abstract

Excellent osteoconductivity or osseointegration of biomaterial is very important for the stability of artificial joints and dental implants in clinical field.Against this background, We have already reported that the low-intensive pulsed ultrasound wave stimulation (LIPUS) could accelerate the bone-like hydroxyapatite precipitation on the bioactive material surface, which corresponds to osseointgration. The purpose of this study was to investigate the difference between the kinds of biomaterials the osseointegration enhanced by LIPUS in vitro. Hydroxyapatite (99.9%) and Bio-active titanium were soaked in simulated body fluid under the LIPUS radiation, and accessed by scanning electron microscope and X-ray diffraction, the mass of precipitation was measured.In a result, bio-active titanium showed the more rich bone-like apatite formation on the surface than hydroxyapatite. These facts suggested that the formation of bone-like apatite might depend on the initial epitaxial nucleation growth on the biomaterial surface.