Filled polymer composites are widely used for automobile, structural and aerospace components owing to their exceptional combination of high specific stiffness and strength. This study presents Taguchi-Deng optimization of tribological parameters such as load, grit size, distance and speed as well as prediction of tribological behaviours of carbon-filled and bronze-filled polytetrafluoroethylene (PTFE) composites using pin on disk configuration. A plan of experiments based on Taguchi L27 (43) orthogonal array (OA) was designed to collect data in a controlled manner. The Taguchi L27 (43) was hybridized with Deng model to produce grey relational grades (GRG) for the multiple response optimization. Analysis of variance (ANOVA) was executed to establish the parameters affecting GRG of the composites. For the prediction of the tribological behaviours of the composites namely coefficient of friction (µ) and specific wear rate (Ks), support vector regression (SVR) was coupled with novel Harris Hawks’ optimization (HHO) and swarm particle optimization (PSO) forming SVR-HHO and SVR-PSO models respectively, were employed. Prediction accuracy of the models were appraised using coefficient of determination (R2), correlation coefficient (R), root mean square error (RMSE) and mean absolute percentage error (MAPE). GRG results revealed that optimum parameters which reduced tribological behaviours were factor combination L3G1D3S3. ANOVA for GRG reveled that grit size with 68.57% ranks as the most influential parameter followed by load with 20.57%, followed by distance having a contribution of 7.78% and finally speed with least contribution of 3.38% for minimum tribological loss. Validation performed using optimum parameters revealed an enhancement of 55% in GRG. Prediction accuracy of the single model increase to 19.50% and 57.08% on the average for hybrid µ and Ks models, respectively. Furthermore, SVR-HHO model indicated the higher prediction accuracy of the tribological behaviours of filled PTFE composites as compared to SVR-PSO model. These findings concluded these metaheuristic models are promising in predicting tribological behaviours of filled PTFE composites and thus can serve as a guide in the design and development of tribological materials.