The complete chloroplast genome of <i>Onosma fuyunensis</i> Y. He &amp; Q.R. Liu and its phylogenetic analysis

Ying, He; Xu, Xuemin; Liu, Quan‐Ru

doi:10.1080/23802359.2020.1861567

Cited by 6 publications

(7 citation statements)

References 10 publications

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“…The analysis demonstrated that the M. sikkimensis chloroplast genome spanned a length of 149,428 bp, and it featured the circular quadripartite typical of chloroplast genomes, consisting of the LSC, SSC, and a pair of IR regions. Gene annotation indicated that the genome contains 112 genes, which include 78 protein-coding genes, 30 tRNA genes, and 4 rRNA genes, which is consistent with the genomic structure and gene quantity observed in the chloroplasts of other species within the Boraginaceae family [47][48][49][50][51]. Introns were crucial for the regulatory mechanisms that control gene expression.…”

Section: Discussionsupporting

confidence: 68%

Comparative Analyses of Complete Chloroplast Genomes of Microula sikkimensis and Related Species of Boraginaceae

Gao,

Chen,

et al. 2024

Genes

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The present study provides a detailed analysis of the chloroplast genome of Microula sikkimensis. The genome consisted of a total of 149,428 bp and four distinct regions, including a large single-copy region (81,329 bp), a small single-copy region (17,261 bp), and an inverted repeat region (25,419 bp). The genome contained 112 genes, including 78 protein-coding genes, 30 tRNA genes, and 4 rRNA genes, and some exhibited duplication in the inverted repeat region. The chloroplast genome displayed different GC content across regions, with the inverted repeat region exhibiting the highest. Codon usage analysis and the identification of simple sequence repeats (SSRs) offer valuable genetic markers. Comparative analysis with other Boraginaceae species highlighted conservation and diversity in coding and noncoding regions. Phylogenetic analysis placed M. sikkimensis within the Boraginaceae family, revealing its distinct relationship with specific species.

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Section: Discussionsupporting

confidence: 68%

Comparative Analyses of Complete Chloroplast Genomes of Microula sikkimensis and Related Species of Boraginaceae

Gao,

Chen,

et al. 2024

Genes

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“… 2022 ), Onosma fuyunensis NC_049569 (He et al. 2021 ), Trigonotis peduncularis MZ911745 (Wu et al. 2022 ), Agastache rugosa MW760849 (Wang et al.…”

Section: Resultsmentioning

confidence: 99%

The complete chloroplast genome of Cynoglossum amabile Stapf & J. R. Drumm., 1906 (Boraginaceae), a traditional Chinese herbal medicine

Zhao

2023

Mitochondrial DNA Part B

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Cynoglossum amabile Stapf & J. R. Drumm., 1906 is a traditional Chinese herbal medicine from southwest China. To better determine its phylogenetic relatedness to other Boraginaceae species, the chloroplast (cp) genome of C. amabile was sequenced. The complete cp genome of C. amabile is 151,532 bp in length, containing a small single-copy (SSC) region with a length of 17,366 bp, a large single-copy (LSC) region with a length of 82,902 bp, and a pair of inverted repeats (IRs) regions each with a length of 25,632 bp. The overall GC content of the cp genome is 37.4%. The maximum-likelihood phylogenetic tree showed that Bothriospermum zeylanicum (J. Jacq.) Druce, 1917 was closely related to C. amabile .

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“…Regarding clinical studies, 2 small-sample cohort studies by He et al showed that bisoprolol 40 and metoprolol 41 increased lumbar spine BMD and reduced the fracture incidence among elderly Chinese men with hypertension who did not take calcium supplements. Khosla et al 42 conducted a randomized controlled trial in 155 postmenopausal American women, excluding those who had taken bisphosphonates.…”

Section: Sbbsmentioning

confidence: 99%

Advanced Progress of the Relationship Between Antihypertensive Drugs and Bone Metabolism

Zhang,

Yin,

Yang

et al. 2023

Hypertension

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Hypertension and osteoporosis are common comorbidities among elderly individuals. Drug therapy has been widely used in clinical practice as the preferred antihypertensive treatment. Therefore, antihypertensive drugs have become some of the most commonly prescribed drugs in healthcare settings. However, antihypertensive drugs have different effects on bone metabolism. The results of animal and clinical studies on the effects of antihypertensive drugs on osteoporosis or fracture risk are controversial and have aroused widespread concern among clinicians. Recent studies found that angiotensin receptor blockers, selective β-adrenergic receptor blockers, and thiazide diuretics might improve bone trabecular number and bone mineral density by stimulating osteoblast differentiation, reducing osteoclast generation, and other mechanism. Furthermore, nonselective β-adrenergic receptor blockers and dihydropyridine calcium channel blockers were found to have no significant relationship with bone mineral density or bone strength, and α-adrenergic receptor blockers and loop diuretics might increase fracture risk by decreasing bone mineral density. This article aimed to review previous animal experiments, clinical studies, and meta-analyses focusing on the effects of different antihypertensive drugs on bone metabolism, and to provide a new approach for the prevention and treatment of osteoporosis.

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The complete chloroplast genome of Onosma fuyunensis Y. He & Q.R. Liu and its phylogenetic analysis

Cited by 6 publications

References 10 publications

Comparative Analyses of Complete Chloroplast Genomes of Microula sikkimensis and Related Species of Boraginaceae

Comparative Analyses of Complete Chloroplast Genomes of Microula sikkimensis and Related Species of Boraginaceae

The complete chloroplast genome of Cynoglossum amabile Stapf & J. R. Drumm., 1906 (Boraginaceae), a traditional Chinese herbal medicine

Advanced Progress of the Relationship Between Antihypertensive Drugs and Bone Metabolism

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