The complex relation between visual complaints and decline in visual, visuoperceptual and cognitive functions in people with multiple sclerosis

Feen, Fleur E. van der; Haan, Gera de; Lijn, Iris van der; Stellingwerf, Catharina; Vrijling, Anne; Heersema, Dorothea; Meilof, Jan F.; Heutink, Joost

doi:10.1080/09602011.2023.2179075

Cited by 3 publications

(7 citation statements)

References 76 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…For this study, we used the data set of a previous study, 4 to address specific additional hypotheses.…”

Section: Methodsmentioning

confidence: 99%

“…The second group consisted of people with MS with no or minimal visual complaints (no complaints often/always, ≤5 complaints sometimes and a discomfort score of ≤4) on the Screening Visual Complaints questionnaire. They were included as a control group in our previous study 4 and were not referred to Royal Dutch Visio. People from the second group were recruited from the MS Centrum Noord Nederland.…”

Section: Methodsmentioning

confidence: 99%

“…A previous study exploring visual complaints in MS suggested that the extent to which visual complaints may be explained by specifically affected ophthalmological, visual or cognitive functions seems limited. 1 , 4 Instead, the results prompted the hypothesis that visual complaints may be indicative of overall reduced cognitive capacity. Reduced contrast sensitivity, visual acuity, sensitivity of the visual field and visual motor speed can indicate a decline in global cognitive functioning.…”

Section: Introductionmentioning

confidence: 99%

“…Reduced contrast sensitivity, visual acuity, sensitivity of the visual field and visual motor speed can indicate a decline in global cognitive functioning. 4 , 5 Thus, besides being a direct consequence of visual function impairment, visual complaints might be explained by more diffuse decline or loss of integrity of a complex functional cerebral network. This diffuse decline refers to a global reduction in cognitive or visual functioning, as opposed to distinctive visual or cognitive function disorders.…”

Section: Introductionmentioning

confidence: 99%

“…We focus on visual acuity, contrast sensitivity and the sensitivity of the monocular visual fields, functions relating to visual complaints and global cognitive decline. 4 We also investigate the relationship between global cognitive decline and smooth pursuit and saccades, visual functions commonly affected in people with MS, but unrelated to visual complaints. We aim to explore the relationship between global cognitive functioning and visual functions, as indicators of loss of integrity of a possibly complex functional cerebral network for vision and cognition.…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

Neurovisual rehabilitation in multiple sclerosis: Why a close integration of low-vision rehabilitation and neuropsychological rehabilitation may be effective for visual complaints

van der Feen,

de Haan,

van der Lijn

et al. 2023

Clin Rehabil

Self Cite

View full text Add to dashboard Cite

Objective The quality of life of people with multiple sclerosis (MS) is often affected by visual complaints. A previous study suggested that visual complaints are not likely to be related to specific visual functions, but by a global decline of cognitive and visual functioning. In this study, we further explore this hypothesis, by investigating the relation between visual functions and global cognitive functioning, aiming to provide recommendations for rehabilitation for visual complaints. Design Cross-sectional study. Setting A rehabilitation centre for partially sighted and blind people and a MS centre at a university hospital. Participants 102 people with MS. Main measure Correlations between assessments of visual functions (acuity, contrast sensitivity, visual field, smooth pursuit and saccades) and composite scores of a neuropsychological assessment (tests with a visual component and without a visual component). Results All composite scores correlated with visual acuity, contrast sensitivity and the sensitivity of the monocular field, but not with smooth pursuit and saccades. Similar patterns were found in various subgroups. Results showed that visual functions that related to visual complaints correlated with a diffuse decline of global cognitive functioning and that visual and cognitive functioning may decline concurrently in people with MS. Conclusions Visual complaints may occur as a result of a diffuse decline of the integrity of a cerebral network involved in vision and cognition. People with MS with visual complaints may benefit from neurovisual rehabilitation, in which low-vision rehabilitation and neuropsychological rehabilitation are closely intertwined.

show abstract

“…For this study, we used the data set of a previous study, 4 to address specific additional hypotheses.…”

Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Neurovisual rehabilitation in multiple sclerosis: Why a close integration of low-vision rehabilitation and neuropsychological rehabilitation may be effective for visual complaints

van der Feen,

de Haan,

van der Lijn

et al. 2023

Clin Rehabil

Self Cite

View full text Add to dashboard Cite

show abstract

The relationship between cognitive function and functional capacity, and cognitive reserve and reaction time in patients with multiple sclerosis

Candiri,

Ramazanoglu,

Talu

et al. 2024

Arq Neuropsiquiatr

View full text Add to dashboard Cite

Background Cognitive dysfunction is frequently seen in multiple sclerosis (MS). However, there are conflicting findings regarding the factors it is associated with. Objective To investigate the relationship between aerobic capacity, strength, disability, depression, fatigue, and cognitive reserve and function. Methods The mobile applications Trail Making Test (TMT A-B), Digit Span Test (DST), Visuospatial Memory Test (VSMT), and Tap Fast were used in the cognitive function evaluation. Functional performance was assessed with the 6-minute walk test (6MWT), 5-Time Sit-to-Sand (5STS) test, and grip strength. Cognitive Reserve Index (CRI), Beck Depression Inventory, Fatigue Severity Scale (FSS), and Nottingham Health Profile were also used. Results A significant difference was found between the MS and control groups only in the 6MWT, STS-5, grip strength, TMT, VSMT, and Tap Fast. Good correlation was found between the TMT-A and 6MWT and physical mobility. A fair correlation was shown between grip strength, energy, and pain status. A good correlation was found between TMT-B and 6MWT, and a fair relationship with disability, cognitive reserve, and pain. Good correlation was observed between the DST and 6MWT, left grip strength, pain, and energy status; fair correlations were found between right grip strength, cognitive reserve, and physical mobility. Good correlation was found between the VSMT and energy. A fair relationship between disability, cognitive reserve, and pain was demonstrated. Good correlation was observed between the Tap Fast score and disability, 5STS, FSS, energy, and physical mobility. A fair relationship was found between pain and social isolation. Conclusion It has been shown that cognitive performance in MS is related to disability, functional performance, cognitive reserve, fatigue, and general health. Trial registration NCT06084182.

show abstract

Reading Difficulties in Parkinson’s Disease: A Stepped Care Model for Neurovisual Rehabilitation

van der Lijn,

de Haan,

van der Feen

et al. 2023

Journal of Parkinson’s Disease

View full text Add to dashboard Cite

Background: People with Parkinson’s disease (PD) frequently experience reading difficulties. Little is known about what functional impairments distinguish people with PD with and without reading difficulties and how these should guide rehabilitation. Objective: To provide concrete advice for an efficient stepped care model for reading difficulties in PD, based on extensive functional assessments. Methods: This study included 74 people with PD in a neurovisual rehabilitation setting who underwent assessment of visual, visuoperceptual, and cognitive functions. Outcomes were compared between those with frequent (RD+; N = 55) and infrequent reading difficulties (RD–; N = 19). Aids and advice provided during rehabilitation were registered. Results: Only a few functions appeared to distinguish RD+ and RD–. Visual functions (i.e., contrast sensitivity, g = 0.76; reading acuity, g = 0.66; visual acuity, g = 0.54) and visuoperceptual functions (i.e., visual attention, g = 0.58, visual motor speed, g = 0.56) showed significant worse scores in RD+ compared to RD–. Aids and advice applied consisted mainly of optimizing refraction, improving lighting, and optimizing text size and spacing. Conclusion: The test battery showed significant differences between RD+ and RD–on only a few tests on visual and visuoperceptual functions. The applied aids and advice matched well with these impairments. Therefore, we recommend a stepped care model, starting with a short test battery on these functions. If this battery indicates functional impairments, this can be followed by standard aids and advice to improve reading. Only in case of insufficient effect additional testing should take place.

show abstract

The complex relation between visual complaints and decline in visual, visuoperceptual and cognitive functions in people with multiple sclerosis

Cited by 3 publications

References 76 publications

Neurovisual rehabilitation in multiple sclerosis: Why a close integration of low-vision rehabilitation and neuropsychological rehabilitation may be effective for visual complaints

Neurovisual rehabilitation in multiple sclerosis: Why a close integration of low-vision rehabilitation and neuropsychological rehabilitation may be effective for visual complaints

The relationship between cognitive function and functional capacity, and cognitive reserve and reaction time in patients with multiple sclerosis

Reading Difficulties in Parkinson’s Disease: A Stepped Care Model for Neurovisual Rehabilitation

Contact Info

Product

Resources

About