The Composition of Grain and Forage from Glyphosate Tolerant Wheat MON 71800 Is Equivalent to That of Conventional Wheat (<i>Triticum aestivum L.</i>)

Obert, Janet C; Ridley, William P.; Schneider, Ronald W.; Riordan, Susan G.; Nemeth, Margaret A.; Trujillo, William A; Breeze, Matthew L.; Sorbet, Roy; Astwood, James D.

doi:10.1021/jf035218u

Cited by 66 publications

(39 citation statements)

References 23 publications

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“…The published studies observed similar results in different GM plants, like potato metabolome (Catchpole et al 2005) and proteome (Lehesranta et al 2005), tomato (Corpillo et al 2004), or transcriptome and metabolome of GM wheat (Baker et al 2006;Baudo et al 2006). Complex analyses of glyphosate tolerant wheat MON 71800 found no significant changes in 88 different components compared with wt plants (Obert et al 2004). Comparative analyses of different GM plants regarding substantial equivalence have been reviewed by Cellini et al (2004).…”

Section: Comparison Of Different Wheat Linesmentioning

confidence: 88%

Flavonoid profiling among wild type and related GM wheat varieties

et al. 2007

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Pleiotropic effects are one of the main concerns regarding genetically modified organisms (GMOs). This includes unintended side effects of the transgene or its genome insertion site on the regulation of other endogenous genes, which could potentially cause the accumulation of different secondary metabolites that may have not only an impact on diet as repeatedly worried by the public but also on the environment. Regarding amount and possible environmental effects, flavonoids represent the most prominent group of secondary metabolites in wheat. Many flavonoids function as signalling or defence molecules. We used a robust and reproducible analytical method to compare the flavonoid content of genetically modified (GM) wheat (Triticum aestivum L., Gramineae) expressing genes that confer increased fungal resistance with their non-GM siblings. The transgenes provide either a broad-spectrum fungal defence (chitinase/glucanase from barley) or bunt-specific resistance by a viral gene (KP4). Significant differences in flavonoid composition were found between different wheat varieties whereas different lines of GM wheat with increased antifungal resistance showed only minor differences in their flavonoid composition relative to their non-GM siblings. In a field test, no significant differences were detectable between infected and non-infected wheat of the same variety regardless of the presence of the transgene. Our results are in agreement with the hypothesis that the transgenes we used to increase wheat defence to fungal pathogens do not interfere with the flavonoid biosynthesis pathway. More significantly, the genetic background resulting from conventional breeding has a direct impact on the biological composition of flavonoids, and thus possibly on the environment.

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Section: Comparison Of Different Wheat Linesmentioning

confidence: 88%

Flavonoid profiling among wild type and related GM wheat varieties

et al. 2007

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“…These studies include assessments of soy (Padgette et al 1996;Taylor et al 1999), corn (Ridley et al 2002;Sidhu et al 2000;Herman et al 2004), cotton (Bertrand et al 2005;Nida et al 1996), rice (Oberdoerfer et al 2005), wheat (Obert et al 2004), andalfalfa (McCann et al 2006). As mentioned earlier, reports of omics studies on biotechnology-derived plants indicate that these are typically more closely related to the isogenic parental strain used in their development than the parental strain is to other members of the same species (see earlier references).…”

Section: Compositional Comparisonsmentioning

confidence: 99%

Metabolomics, metabolic diversity and genetic variation in crops

2007

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The metabolome represents a critical aspect of a plant's physiology, growth characteristics and, ultimately, economic value. Metabolic changes underpin plant development and responses to applied stresses, whilst quality traits in many important crops and ornamental plants are dependent on metabolic composition. It is also frequently reasoned that metabolic information reflects biological endpoints more accurately than transcript or protein analysis. As such, the science of metabolomics has proven to be of increasing popularity in assessing genotypic and phenotypic diversity in plants, in defining biochemical changes associated with developmental changes during plant growth and, increasingly, in compositional comparisons. The postulated value of this metabolic information resides primarily in its potential to support breeding and selection of novel yield-enhanced and nutritionally improved crops. Plants display remarkable genetic plasticity which has served to facilitate the development of an extraordinary range of genetically distinct and metabolically diverse cultivars for any given plant species. Despite concerns regarding potential loss of genetic diversity through domestication, genetic resources still exist through wild and exotic germplasms. Additionally, emerging biotechnological approaches such as RNAi silencing and the transgenic modification of regulatory genes offer new and fascinating opportunities for enhancing diversity and eliciting trait improvements. This review is intended to promote the view that metabolomics, through comparative assessments of metabolic diversity in domesticated and non-domesticated plants, and through evaluations of the compositional impact of metabolic engineering efforts can support breeding programmes designed to elicit trait improvements.

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“…Conversely, the same lines showed elevation in proline and ␥ -aminobutyric acid (GABA) at the alternative environment. Obert et al (2004) also failed to find any significant differences between grain field plots of herbicide-resistant and control lines using a combined GC and LC approach.…”

Section: Grain Crops 731 the Cerealsmentioning

confidence: 94%

Crops and Tasty, Nutritious Food – How Can Metabolomics Help?

Stewart¹,

Shepherd²,

Hall

et al. 2011

Annual Plant Reviews Volume 43

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Food quality, security and safety have become topics of considerable recent interest. With a rapidly growing world population, entailing an everexpanding requirement for food, and with the global consumer making higher and better-informed demands on our crop and food producers, much attention is being given to how we can meet all these growing needs. Crop growers and food processors alike are already looking at state-of-the-art technologies such as metabolomics as a source of new inroads into the generation of detailed knowledge on the biochemical composition of crop products and how they change during transport, storage and industrial processing. All the steps in the food production chain, from the moment the plant breeder makes the first cross to the canning factory delivering to the supermarket distributor, have potentially significant influence on the quality of the final product the consumer places on the kitchen table. Metabolomics of crop plants and plant products is already being widely applied and is generating new information on the complexity of food composition. In this chapter, some of the main subjects of recent research, concerning both fresh and processed materials, are covered. Emphasis has been laid on technological

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The Composition of Grain and Forage from Glyphosate Tolerant Wheat MON 71800 Is Equivalent to That of Conventional Wheat (Triticum aestivum L.)

Cited by 66 publications

References 23 publications

Flavonoid profiling among wild type and related GM wheat varieties

Flavonoid profiling among wild type and related GM wheat varieties

Metabolomics, metabolic diversity and genetic variation in crops

Crops and Tasty, Nutritious Food – How Can Metabolomics Help?

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