The concentration of radon gas in air-conditioned indoor Air quality can increase the potential of lung cancer

Ratnawati, I Gusti Agung Ayu; Sutapa, Gusti Ngurah; Ratini, Ni Nyoman

doi:10.29332/ijpse.v2n2.169

Cited by 18 publications

(20 citation statements)

References 1 publication

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“…Extreme oxidative stress on the hippocampus and amygdala can impair hippocampal synaptic plasticity, causing memory deficits (28,29). According to reports, phenolics, flavonoids, steroids, alkaloids, saponins, and terpenoids in plants have medical uses (30).…”

Section: Discussionmentioning

confidence: 99%

Neuroprotective effect of derris indica seed extract attenuates amyloid beta plaques induce Alzheimer’s in mice model

Kuruvella

Yellu

2022

ijhs

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The progression of Alzheimer's disease type dementia is carried on by the neurotoxic effects of amyloid beta (Aβ25-35) peptide accumulation. The hypothalamic-pituitary-adrenal(HPA) axis malfunctions and leads to higher levels of amyloid beta(Aβ) accumulation. In this work, we looked at how Derris indica extract affected mice brains that had undergone neurodegeneration caused by the Aβ. Derris indica seed extract(DISE) were administered to mice over the course of 21 days in two dosages (50 mg/kg and 100 mg/kg). On the 21st day, tests for spatial learning, habituation memory, short-and long-term memory, and stepdown inhibitory responses were carried out. Pro-and anti-inflammatory cytokines and antioxidants were assessed in brain tissues. A significant (p<0.01) improvement in habituation memory and the step-down inhibitory avoidance test was seen after receiving the DISE therapy, reduced escape delay considerably (p<0.01) enhanced cognitive progress in spatial learning. DISE may have an impact on neuroprotection as seen by the significant (p<0.01) decrease in proinflammatory and enhancement in IL-10 along with improved antioxidant indicators. According to investigations, the DISE enhance cognition by controlling neuro-inflammation and neuroimmune function, which are both controlled by the HPA axis, which mitigates stress. DISE might be promising therapeutics for neurodegeneration disorders such as AD.

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Section: Discussionmentioning

confidence: 99%

Neuroprotective effect of derris indica seed extract attenuates amyloid beta plaques induce Alzheimer’s in mice model

Kuruvella

Yellu

2022

ijhs

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“…However, in their study overweight, obesity & hypertension were not excluded, which create hyperuricemia as confounding factors. [24] The treatment of hyperuricemia with hypouricemic drugs [25] has been concluded by Katsiki N. et al in their review of diabetes and its complications [26]. Keenan T., et al have concluded that increased serum urate levels are not associated with type 2 diabetes, coronary heart disease, ischemic stroke or hypertension.…”

Section: Discussionmentioning

confidence: 99%

correlation of serum uric acid levels with type II diabetic patients

Singh

Aggarwal

Batra

2022

ijhs

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Aim: To correlate diabetes patients' blood uric acid levels with their duration of diabetes. Materials and methods: This study was conducted on 100 diabetic patients(30-50 years).diabetic patients with no history of any other systemic complications and metabolic disorders like obesity and gout . Each diabetic patient was subjected to detailed general examination. A biochemical investigation for fasting serum uric acid levels estimated. Results: A positive correlation present between SUA and duration of type 2 diabetes is statistically significant. As the duration of diabetes increases than there is an increase in the serum uric acid concentration in type 2 diabetes patients (r = +0.630,p<0.001). Conclusion: Drugs that reduce the serum uric acid level may become effective in preventing the development and prognosis of insulin resistance, a major factor in type 2 diabetes. The significant positive correlation between serum uric acid and the duration of type 2 diabetes suggests the uric acid acts as an independent biochemical marker for type 2 diabetes prognosis.

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“…A number of studies considered that the greater platelet consumption is owing to dispersed intravascular coagulation while other proposed it as immune mechanism. 9,10 The degree of thrombocytopenia increases with severity of preeclampsia. Lesser the number of platelets count, greater the number of maternal and fetal mortality.…”

Section: Table 1 Biochemical/haematological and Other Parameters Of T...mentioning

confidence: 99%

Comparison of biochemical/haematological parameters in healthy vs preeclamptic females

Samad¹,

Afshan²,

Mehmood³

et al. 2022

ijhs

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Objectives: To evaluate and compare the Biochemical/Haematological parameters in healthy (pregnant subjects) vs preeclamptic females. Methodology: This descriptive cross-sectional study was planned/conducted at IBMS KMU Peshawar and the data was collected from the Dept. of Gynaecology & Obstetrics-Lady Reading Hospital Peshawar, from June 2019 to July 2020. One hundred thirty-eight pregnant subjects between the gestational ages of 26-30 weeks were included in the study. The subjects were divided into two cohorts; Patients with preeclampsia (Group I N=92) and a Normotensive Control Group; women with normal pregnancy (Control group N=46). Blood from the subjects was checked for Haemoglobin (Hb) and Platelet (PLT) levels and Body Mass Index (BMI) among other parameters. Blood was taken and analysed at the Hospital Lab via Cobas 6000 analyser. Data was analysed using SPSS version 26.0 for MacBook Pro. Results: Body mass index of PE group was significantly higher compared to normal group (p<0.001). Similarly, mean platelet counts and hemoglobin in PE group was lower as compared to normo-tensive group and the differences were statistically significant (p<0.05). There was no significant difference in mean gestational age (weeks) between the two groups (27.83 ± 0.95 vs 27.78 ± 1.07, p= 0.33) was observed.

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The concentration of radon gas in air-conditioned indoor Air quality can increase the potential of lung cancer

Cited by 18 publications

References 1 publication

Neuroprotective effect of derris indica seed extract attenuates amyloid beta plaques induce Alzheimer’s in mice model

Neuroprotective effect of derris indica seed extract attenuates amyloid beta plaques induce Alzheimer’s in mice model

correlation of serum uric acid levels with type II diabetic patients

Comparison of biochemical/haematological parameters in healthy vs preeclamptic females

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