The concentrations of bioelements in the hair samples of Jordanian children who stutter

Alqhazo, Mazin; Rashaid, Ayat Bani

doi:10.1016/j.ijporl.2018.06.045

Cited by 14 publications

(26 citation statements)

References 34 publications

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“…Once in the bloodstream, V is distributed and stored in different tissues and among the various tissues, with the bioaccumulation in hair being of interest as it represents a biological substrate that is easy to collect [ 20 ]. In humans, some studies have shown V concentrations in the scalp hair of healthy adults due to potential bioaccumulation of this element, and in horses, no study has been conducted to evaluation bioaccumulation in hair [ 21 ]. Our results show higher V levels in whole blood and mane than serum and tail.…”

Section: Discussionmentioning

confidence: 99%

Bioaccumulation of Mineral Elements in Different Biological Substrates of Athletic Horse from Messina, Italy

Fazio

Gugliandolo

Nava

et al. 2020

Animals

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The objective of this study was to evaluate the levels and the potential bioaccumulation of vanadium (V), chromium (Cr), cobalt (Co), copper (Cu), zinc (Zn), cadmium (Cd), lead (Pb), and bismuth (Bi) in horses from the industrial risk area of Sicily (Italy). Different biological substrates (whole blood, serum; tail and mane) and samples of hay, concentrate and water provided to the horses were processed by means of Thermo Scientific iCAP-Q ICP–MS spectrometer for mineral concentration. One-way analysis of variance (ANOVA) was applied to show the differences in various trace elements in the biological substrates. Pearson’s test was applied to evaluate the correlation of mineral concentrations between whole blood and serum; and tail and mane. The results showed statistical differences of tested mineral elements among biological substrates; Cr whole blood concentrations were negatively correlated with serum concentrations and a positive correlation between whole blood and serum was observed for Cd and Bi. This latter also showed a positive correlation between mane and tail. The concentrations of V, Cr, and Pb in tail with serum and whole blood samples were negatively correlated, while the concentrations of Cd in tail and serum samples were positively correlated. Minerals had a non-homogenous distribution in the organism, showing different concentrations in the biological substrates.

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Section: Discussionmentioning

confidence: 99%

Bioaccumulation of Mineral Elements in Different Biological Substrates of Athletic Horse from Messina, Italy

Fazio

Gugliandolo

Nava

et al. 2020

Animals

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“…It should be noted that the recommended daily allowances (RDA) for Se should be at the level of 60-70 μg/ day [162]. Concentrations of Se have, however, been examined in two studies using samples of blood and hair [163].…”

Section: Se Status In Jordanmentioning

confidence: 99%

“…It should be noted that the recommended daily allowances (RDA) for Se should be at the level of 60–70 μg/day [ 162 ]. Concentrations of Se have, however, been examined in two studies using samples of blood and hair [ 163 ]. Blood concentrations of about 187 μg/L were considered to be comparatively large in nonsmokers [ 164 ].…”

Section: Se Status In Jordanmentioning

confidence: 99%

A Comprehensive Review on Selenium and Its Effects on Human Health and Distribution in Middle Eastern Countries

Kieliszek

Bano

Zare

2021

Biol Trace Elem Res

105

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Selenium (Se) is an important microelement with numerous positive effects on human health and diseases. It is important to specify that the status and consumption of Se are for a specific community as the levels of Se are extremely unpredictable between different populations and regions. Our existing paper was based on the impacts of Se on human health and disease along with data on the Se levels in Middle Eastern countries. Overall, the findings of this comprehensive review show that the consumption and levels of Se are inadequate in Middle Eastern nations. Such findings, together with the growing awareness of the importance of Se to general health, require further work primarily on creating an acceptable range of blood Se concentration or other measures to determine optimal Se consumption and, consequently, to guarantee adequate Se supplementation in populations at high risk of low Se intake.

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“…Also, studies have identified that the human colostrum and breast milk generally contained less than 1.0 ng/g of vanadium of dry weight [143]. Additionally, vanadium concentrations in scalp hair of healthy adults have been found in the range of 433 pg/g to 90 ng/g [144–147]. In general, the evidence has demonstrated that the most tissues contain less than 10 ng vanadium/g wet weight.…”

Section: Vanadium Tissue Distribution and Cellular Uptake/incorporatimentioning

confidence: 99%

Vanadium in Biological Action: Chemical, Pharmacological Aspects, and Metabolic Implications in Diabetes Mellitus

Treviño

Díaz

Sánchez-Lara

et al. 2018

Biol Trace Elem Res

252

126

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Vanadium compounds have been primarily investigated as potential therapeutic agents for the treatment of various major health issues, including cancer, atherosclerosis, and diabetes. The translation of vanadium-based compounds into clinical trials and ultimately into disease treatments remains hampered by the absence of a basic pharmacological and metabolic comprehension of such compounds. In this review, we examine the development of vanadium-containing compounds in biological systems regarding the role of the physiological environment, dosage, intracellular interactions, metabolic transformations, modulation of signaling pathways, toxicology, and transport and tissue distribution as well as therapeutic implications. From our point of view, the toxicological and pharmacological aspects in animal models and humans are not understood completely, and thus, we introduced them in a physiological environment and dosage context. Different transport proteins in blood plasma and mechanistic transport determinants are discussed. Furthermore, an overview of different vanadium species and the role of physiological factors (i.e., pH, redox conditions, concentration, and so on) are considered. Mechanistic specifications about different signaling pathways are discussed, particularly the phosphatases and kinases that are modulated dynamically by vanadium compounds because until now, the focus only has been on protein tyrosine phosphatase 1B as a vanadium target. Particular emphasis is laid on the therapeutic ability of vanadium-based compounds and their role for the treatment of diabetes mellitus, specifically on that of vanadate-and polioxovanadate-containing compounds. We aim at shedding light on the prevailing gaps between primary scientific data and information from animal models and human studies.

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The concentrations of bioelements in the hair samples of Jordanian children who stutter

Cited by 14 publications

References 34 publications

Bioaccumulation of Mineral Elements in Different Biological Substrates of Athletic Horse from Messina, Italy

Bioaccumulation of Mineral Elements in Different Biological Substrates of Athletic Horse from Messina, Italy

A Comprehensive Review on Selenium and Its Effects on Human Health and Distribution in Middle Eastern Countries

Vanadium in Biological Action: Chemical, Pharmacological Aspects, and Metabolic Implications in Diabetes Mellitus

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