The concentrations of serum, plasma and platelet BDNF are all increased by treadmill VO2max performance in healthy college men

Hyun-Chul, Cho; Kim, Jong-Kyu; Kim, Sung-Yeon; Son, Yeon Hee; Lee, Nam‐Ju; Jung, Soo Yeon

doi:10.1016/j.neulet.2012.05.025

Cited by 115 publications

(102 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Nevertheless, hippotherapy showed a positive tendency to improve BDNF levels in the HRG and, based on this result, we can expect that increased frequency in hippotherapy for ADHA children may have a significant positive effect on neuroplasticity. It is a known fact that the BDNF level is subordinate to blood concentration changes in the recovery phase due to intensity and frequency of exercise and platelet counts play an important role in changing BDNF levels during exercise [21,22]. Moreover, the BDNF level is an essential factor for the neuronal system and directly affects energy metabolism in the central and peripheral nervous area [23].…”

Section: Discussionmentioning

confidence: 99%

Effects of hippotherapy on brain function, BDNF level, and physical fitness in children with ADHD

Lee

Park

Kim

2015

J. Exerc. Nutr, Biochem.

Self Cite

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

Effects of hippotherapy on brain function, BDNF level, and physical fitness in children with ADHD

Lee

Park

Kim

2015

J. Exerc. Nutr, Biochem.

Self Cite

View full text Add to dashboard Cite

“…For studies involving healthy human subjects such as this one, the supposition remains that the brain is the primary source of urinary BDNF. Still, in order to establish the reliability of urine as an independent peripheral biomarker, it will be important to track urinary BDNF levels alongside blood-borne levels [for protocol examples, see [45]].…”

Section: Discussionmentioning

confidence: 99%

Urinary Brain-Derived Neurotrophic Factor as a Biomarker of Executive Functioning

Koven

Collins

2014

Neuropsychobiology

View full text Add to dashboard Cite

Background/Aims: Neurotrophins such as brain-derived neurotrophic factor (BDNF) are vital for neuronal survival and adaptive plasticity. With high BDNF gene expression in the prefrontal cortex, BDNF is a potential regulatory factor for building and maintaining cognitive reserves. Recent studies suggest that individual differences in executive functioning, a broad cognitive domain reliant upon frontal lobe structure and function, are governed in part by variance in BDNF polymorphisms. However, as neurogenetic data are not necessarily indicative of in vivo neurochemistry, this study examines the relationship between executive functioning and the neurotransmitter by measuring peripheral BDNF levels. Methods: Fifty-two healthy young adults completed a battery of standardized executive function tests. BDNF levels, adjusted for creatinine, were quantified with enzyme-linked immunosorbent assay of urine samples taken at the time of testing. Results: BDNF concentration was positively associated with cognitive flexibility but had no relationship with working memory, abstract reasoning/planning, self-monitoring/response inhibition, or fluency. Conclusions: These results individuate cognitive flexibility as the specific facet of executive functioning associated with in vivo BDNF levels. This study also validates urinary BDNF as a peripheral biomarker of cognition in healthy adults.

show abstract

“…Plasma showed the most variable results regardless platelets presence (187). Resting BDNF levels were inversely associated with the cardiorespiratory fitness (174).…”

Section: Pre-analytical Factorsmentioning

confidence: 94%

“…Indeed, exercise promotes the release of BDNF from brain (through the blood-brain barrier) and from muscles and increases BDNF blood levels in healthy individuals. The increase of circulating BDNF is directly proportional to exercise intensity (172)(173)(174). BDNF increases induced by exercise accounts for at least a portion of the neuroprotective effects of exercise (175).…”

Section: Brain- Neuron- Glial Cell Line-derived Neurotrophic Factormentioning

confidence: 99%

Measuring myokines with cardiovascular functions: pre-analytical variables affecting the analytical output

Lombardi¹,

Sansoni²,

Banfi³

2017

Ann. Transl. Med.

View full text Add to dashboard Cite

Abstract:In the last few years, a growing number of molecules have been associated to an endocrine function of the skeletal muscle. Circulating myokine levels, in turn, have been associated with several pathophysiological conditions including the cardiovascular ones. However, data from different studies are often not completely comparable or even discordant. This would be due, at least in part, to the whole set of situations related to the preparation of the patient prior to blood sampling, blood sampling procedure, processing and/or store. This entire process constitutes the pre-analytical phase. The importance of the preanalytical phase is often not considered. However, in routine diagnostics, the 70% of the errors are in this phase. Moreover, errors during the pre-analytical phase are carried over in the analytical phase and affects the final output. In research, for example, when samples are collected over a long time and by different laboratories, a standardized procedure for sample collecting and the correct procedure for sample storage are acknowledged. In this review, we discuss the pre-analytical variables potentially affecting the measurement of myokines with cardiovascular functions.

show abstract

The concentrations of serum, plasma and platelet BDNF are all increased by treadmill VO2max performance in healthy college men

Cited by 115 publications

References 26 publications

Effects of hippotherapy on brain function, BDNF level, and physical fitness in children with ADHD

Effects of hippotherapy on brain function, BDNF level, and physical fitness in children with ADHD

Urinary Brain-Derived Neurotrophic Factor as a Biomarker of Executive Functioning

Measuring myokines with cardiovascular functions: pre-analytical variables affecting the analytical output

Contact Info

Product

Resources

About